Literature DB >> 79032

Increased unsaturated transcobalamin II in active autoimmune disease.

M Fràter-Schröder, W H Hitzig, P J Grob, A B Kenny.   

Abstract

Measurements of transcobalamin II (T.C. II) concentrations in 26 patients with lupus erythematosus, 4 with dermatomyositis, 2 with autoimmune haemolytic anaemia, and in 40 immunosuppressed renal-transplant patients showed that T.C. II levels were raised during active phases of autoimmune disease. Changes in T.C. II levels correlated better with the clinical course of autoimmune disease than did changes in C3, the titre of antinuclear antibody, or native D.N.A.-binding capacity.

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Year:  1978        PMID: 79032     DOI: 10.1016/s0140-6736(78)91747-6

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  3 in total

Review 1.  Cellular uptake of cobalamin: transcobalamin and the TCblR/CD320 receptor.

Authors:  Edward V Quadros; Jeffrey M Sequeira
Journal:  Biochimie       Date:  2013-02-14       Impact factor: 4.079

2.  Fraction of total plasma vitamin B12 bound to transcobalamin correlates with cognitive function in elderly Latinos with depressive symptoms.

Authors:  Marjorie G Garrod; Ralph Green; Lindsay H Allen; Dan M Mungas; William J Jagust; Mary N Haan; Joshua W Miller
Journal:  Clin Chem       Date:  2008-05-01       Impact factor: 8.327

Review 3.  Genetic patterns of transcobalamin II and the relationships with congenital defects.

Authors:  M Fràter-Schröder
Journal:  Mol Cell Biochem       Date:  1983       Impact factor: 3.396

  3 in total

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