Literature DB >> 7902980

Chronic nicotine treatment potentiates behavioral responses to dopaminergic drugs in rats.

K Suemaru1, Y Gomita, K Furuno, Y Araki.   

Abstract

In the present study, the behavioral effects of apomorphine, methamphetamine, and haloperidol were examined in nicotine-treated rats. All animals were SC administered nicotine at a dose of 0.5 mg/kg or saline once daily for 14 days. Hyperlocomotion induced by apomorphine (0.2 mg/kg, IP) and methamphetamine (1.0 mg/kg, IP) was greater in nicotine-treated rats than in control rats. Stereotyped behaviors induced by apomorphine (1.0 mg/kg, IP) and methamphetamine (5.0 mg/kg, IP) were also potentiated in nicotine-treated rats. However, the incidence of catalepsy induced by haloperidol (0.25-1.5 mg/kg, IP) was slightly lower in nicotine-treated rats. These results suggest that chronic nicotine treatment may increase the susceptibility of the dopaminergic system to dopaminergic drugs.

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Year:  1993        PMID： 7902980     DOI： 10.1016/0091-3057(93)90329-r

Source DB:  PubMed          Journal:  Pharmacol Biochem Behav        ISSN： 0091-3057            Impact factor:   3.533


  10 in total

1.  The sensitizing effect of acute nicotine on amphetamine-stimulated behavior and dopamine efflux requires activation of β2 subunit-containing nicotinic acetylcholine receptors and glutamate N-methyl-D-aspartate receptors.

Authors:  Myung N Kim; Emily M Jutkiewicz; Minjia Zhang; Margaret E Gnegy
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2.  Effects of environmental conditioning on the development of nicotine sensitization: behavioral and neurochemical analysis.

Authors:  M S Reid; L B Ho; S P Berger
Journal:  Psychopharmacology (Berl)       Date:  1996-08       Impact factor: 4.530

Review 3.  Interactions between nicotine and drugs of abuse: a review of preclinical findings.

Authors:  Stephen J Kohut
Journal:  Am J Drug Alcohol Abuse       Date:  2016-09-02       Impact factor: 3.829

Review 4.  Recent advances in understanding nicotinic receptor signaling mechanisms that regulate drug self-administration behavior.

Authors:  Luis M Tuesta; Christie D Fowler; Paul J Kenny
Journal:  Biochem Pharmacol       Date:  2011-06-29       Impact factor: 5.858

5.  Nicotine exposure beginning in adolescence enhances the acquisition of methamphetamine self-administration, but not methamphetamine-primed reinstatement in male rats.

Authors:  Joseph A Pipkin; Graham J Kaplan; Christopher P Plant; Shannon E Eaton; Susan M Gil; Arturo R Zavala; Cynthia A Crawford
Journal:  Drug Alcohol Depend       Date:  2014-07-03       Impact factor: 4.492

6.  Nicotine and amphetamine acutely cross-potentiate their behavioral and neurochemical responses in female Holtzman rats.

Authors:  Emily M Jutkiewicz; Danielle M Nicolazzo; Myung N Kim; Margaret E Gnegy
Journal:  Psychopharmacology (Berl)       Date:  2008-06-20       Impact factor: 4.530

7.  Locomotor activation and dopamine release produced by nicotine and isoarecolone in rats.

Authors:  P Whiteaker; H S Garcha; S Wonnacott; I P Stolerman
Journal:  Br J Pharmacol       Date:  1995-10       Impact factor: 8.739

8.  Nicotine and methamphetamine share discriminative stimulus effects.

Authors:  Michael B Gatch; Elva Flores; Michael J Forster
Journal:  Drug Alcohol Depend       Date:  2007-10-24       Impact factor: 4.492

9.  Chronic co-administration of nicotine and methamphetamine causes differential expression of immediate early genes in the dorsal striatum and nucleus accumbens of rats.

Authors:  F Saint-Preux; L R Bores; I Tulloch; B Ladenheim; R Kim; P K Thanos; N D Volkow; J L Cadet
Journal:  Neuroscience       Date:  2013-04-03       Impact factor: 3.590

Review 10.  Exposure to nicotine and sensitization of nicotine-induced behaviors.

Authors:  P Vezina; D S McGehee; W N Green
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2007-09-01       Impact factor: 5.067
  10 in total

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