Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Stem cell transplantation.

Literature DB >> 7901944

Stem cell transplantation.

Abstract

Modern physicians desire not only to treat but to cure congenital diseases. In a wide variety of diseases, bone marrow transplantation can be the tool of final cure. The limitations and risks of this procedure have motivated researchers to search for an earlier and safer method of treatment. Special features of fetal immune systems make it possible to perform the transplantation during fetal life using fetal hematopoietic stem cells, thus avoiding many of the side effects of bone marrow transplantation in neonatal life. We review the experimental work done with animal models in this field and the human trials that have been published recently.

Entities: Disease Species

Mesh：

Year: 1993 PMID： 7901944 PMCID： PMC1011350

Source DB: PubMed Journal: West J Med ISSN： 0093-0415

Keyword Cloud
References

26 in total

Stem cell transplantation.

1. Actively acquired tolerance of foreign cells.

2. Modification of acute irradiation injury in mice and guinea-pigs by bone marrow injections.

3. Bone-marrow transplantation in a patient with the Wiskott-Aldrich syndrome.

4. Bone marrow transplantation: progress and problems.

5. Chimerism following fetal transfusion. Report of leucocyte hybridization and infant with acute lymphocytic leukaemia.

6. Successful fetal liver transplantation in a child with severe combined immunodeficiency.

7. Rationale and results of in utero transplants of stem cells in humans.

8. In utero transplantation of stem cells in humans: immunological aspects and clinical follow-up of patients.

9. Donor haemoglobin in anaemic mice of the W-series transplanted with haematopoietic tissue from an unrelated donor.

10. Experimental chimerism in a genetic defect in the house mouse Mus musculus.