Literature DB >> 7901877

Recent developments in alcoholism:opioid peptides.

J C Froehlich1, T K Li.   

Abstract

A large body of evidence indicates that the endogenous opioid system plays an important role in maintaining alcohol drinking behavior. Research is reviewed indicating that the reinforcing properties of alcohol which lead to continued and repeated bouts of drinking are due, in part, to alcohol-induced activation of the endogenous opioid system. Opioid receptor antagonists decrease alcohol craving, alcohol consumption, and loss of control over drinking. The potential of opioid receptor antagonists to improve treatment outcome in comprehensive relapse prevention programs is discussed.

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Year:  1993        PMID： 7901877

Source DB:  PubMed          Journal:  Recent Dev Alcohol        ISSN： 0738-422X


  8 in total

1.  Combining naltrexone and prazosin in a single oral medication decreases alcohol drinking more effectively than does either drug alone.

Authors:  Janice C Froehlich; Brett J Hausauer; Dennis D Rasmussen
Journal:  Alcohol Clin Exp Res       Date:  2013-07-22       Impact factor: 3.455

Review 2.  Pharmacokinetic and pharmacodynamic principles of illicit drug use and treatment of illicit drug users.

Authors:  D I Quinn; A Wodak; R O Day
Journal:  Clin Pharmacokinet       Date:  1997-11       Impact factor: 6.447

3.  Evidence that Melanocortin Receptor Agonist Melanotan-II Synergistically Augments the Ability of Naltrexone to Blunt Binge-Like Ethanol Intake in Male C57BL/6J Mice.

Authors:  Montserrat Navarro; Francisca Carvajal; Jose Manuel Lerma-Cabrera; Inmaculada Cubero; Mitchell J Picker; Todd E Thiele
Journal:  Alcohol Clin Exp Res       Date:  2015-06-24       Impact factor: 3.455

Review 4.  Clinical issues related to the costs of alcoholism.

Authors:  M O Howard; R W McGuffin; A J Saxon; K L Sloan; R D Walker
Journal:  Pharmacoeconomics       Date:  1996-02       Impact factor: 4.981

5.  Decreased immunoreactivity of the polypeptide precursor pro-opiomelanocortin (POMC) and the prohormone convertase pc1/3 after chronic ethanol exposure in Sprague-Dawley rats.

Authors:  Montserrat Navarro; Inmaculada Cubero; Todd E Thiele
Journal:  Alcohol Clin Exp Res       Date:  2012-10-10       Impact factor: 3.455

6.  Bupropion, Alone and in Combination with Naltrexone, Blunts Binge-Like Ethanol Drinking and Intake Following Chronic Intermittent Access to Ethanol in Male C57BL/6J Mice.

Authors:  Montserrat Navarro; Kendall L Luhn; Alexey B Kampov-Polevoy; James C Garbutt; Todd E Thiele
Journal:  Alcohol Clin Exp Res       Date:  2019-03-19       Impact factor: 3.455

7.  Ethanol-induced increase of agouti-related protein (AgRP) immunoreactivity in the arcuate nucleus of the hypothalamus of C57BL/6J, but not 129/SvJ, inbred mice.

Authors:  Inmaculada Cubero; Montserrat Navarro; Francisca Carvajal; Jose Manuel Lerma-Cabrera; Todd E Thiele
Journal:  Alcohol Clin Exp Res       Date:  2010-01-26       Impact factor: 3.455

8.  The delta opioid receptor antagonist naltrindole attenuates both alcohol and saccharin intake in rats selectively bred for alcohol preference.

Authors:  S Krishnan-Sarin; S L Jing; D L Kurtz; M Zweifel; P S Portoghese; T K Li; J C Froehlich
Journal:  Psychopharmacology (Berl)       Date:  1995-07       Impact factor: 4.530
  8 in total

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