H E Grossniklaus1, J I Lim. 1. Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia.
Abstract
BACKGROUND: There is a spectrum of benign and malignant ciliary body tumors that can be classified by histopathologic examination. METHODS: A 55-year-old woman with a history of ovarian carcinoma underwent excision of a ciliary body tumor in her right eye. The tumor was submitted for light microscopic, immuno-histochemical, and ultrastructural examination. RESULTS: The tumor was composed of sheets and cords of cells with bland cytologic features. Immunohistochemical stains were positive for S-100 protein and vimentin in tumor cells. Ultrastructural examination showed intercellular junctions and thick basement membrane within the tumor. CONCLUSION: The tumor was classified as an adenoma of the ciliary body nonpigmented epithelium, a benign tumor with variable histopathologic features.
BACKGROUND: There is a spectrum of benign and malignant ciliary body tumors that can be classified by histopathologic examination. METHODS: A 55-year-old woman with a history of ovarian carcinoma underwent excision of a ciliary body tumor in her right eye. The tumor was submitted for light microscopic, immuno-histochemical, and ultrastructural examination. RESULTS: The tumor was composed of sheets and cords of cells with bland cytologic features. Immunohistochemical stains were positive for S-100 protein and vimentin in tumor cells. Ultrastructural examination showed intercellular junctions and thick basement membrane within the tumor. CONCLUSION: The tumor was classified as an adenoma of the ciliary body nonpigmented epithelium, a benign tumor with variable histopathologic features.
Authors: Elli Harford; Jane M Palmer; William J Glasson; Sunil K Warrier; Kevin J Whitehead; Kelly M Brooks; Peter A Johansson; Nicholas K Hayward; Lindsay A McGrath Journal: Int J Retina Vitreous Date: 2022-04-01