| Literature DB >> 7899553 |
E E Budzinski1, J D Dawidzik, J C Wallace, H G Freund, H C Box.
Abstract
This report extends our investigation of double base lesions produced by irradiation of DNA model compounds. Studies of d(CpGpTpA) X-irradiated in oxygenated aqueous solution show that two of the five principal products are oligomers having adjacent bases damaged. In these oligomers guanine is hydroxylated at the 8-position and an adjacent pyrimidine is degraded to a formamido remnant.Entities:
Mesh：
Substances：
Year: 1995 PMID： 7899553
Source DB: PubMed Journal: Radiat Res ISSN： 0033-7587 Impact factor: 2.841