Literature DB >> 7898749

The rat preprotachykinin-A promoter is regulated in PC12 cells by the synergistic action of multiple stimuli.

C F Morrison1, J McAllister, V Lyons, K Chapman, J P Quinn.   

Abstract

We demonstrate in PC12 cells that although nerve growth factor, forskolin or potassium-evoked depolarisation independently induced minimal or no expression from the rat preprotachykinin-A gene (rPPT) promoter linked to a reporter gene, exposure of the cells to various combinations of these stimuli specifically activated the rPPT promoter in transient transfection assays.

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Year:  1994        PMID： 7898749     DOI： 10.1016/0304-3940(94)90573-8

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  5 in total

1.  Novel cell lines for the analysis of preprotachykinin A gene expression identify a repressor domain 3' of the major transcriptional start site.

Authors:  C E Fiskerstrand; P Newey; B Ebrahimi; L Gerrard; P Harrison; G P McGregor; J P Quinn
Journal:  Biochem J       Date:  1999-08-01       Impact factor: 3.857

2.  An upstream stimulatory factor (USF) binding motif is critical for rat preprotachykinin-A promoter activity in PC12 cells.

Authors:  J M Paterson; C F Morrison; S C Mendelson; J McAllister; J P Quinn
Journal:  Biochem J       Date:  1995-09-01       Impact factor: 3.857

3.  Lithium chloride regulation of the substance P encoding preprotachykinin a, Tac1 gene in rat hippocampal primary cells.

Authors:  Kate Haddley; Eleanor Mary Spencer; Sylvia Argiroula Vasiliou; Mark Howard; Thimmasettappa Thippeswamy; Vivien Jill Bubb; John P Quinn
Journal:  J Mol Neurosci       Date:  2010-08-06       Impact factor: 3.444

4.  Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones.

Authors:  Lynne Shanley; Marissa Lear; Scott Davidson; Ruth Ross; Alasdair MacKenzie
Journal:  J Neuroinflammation       Date:  2011-02-04       Impact factor: 8.322

5.  A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample.

Authors:  Camila Guindalini; Mark Howard; Kate Haddley; Ronaldo Laranjeira; David Collier; Nik Ammar; Ian Craig; Colin O'Gara; Vivian J Bubb; Tiffany Greenwood; John Kelsoe; Phil Asherson; Robin M Murray; Adauto Castelo; John P Quinn; Homero Vallada; Gerome Breen
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-14       Impact factor: 11.205
  5 in total

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