Literature DB >> 7896581

Immunocytochemical localization of AMPA selective glutamate receptor subunits in the rat cochlea.

H Kuriyama1, O Jenkins, R A Altschuler.   

Abstract

The localization of subunits of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) selective glutamate receptor, termed Glutamate receptor (GluR) was examined in the rat cochlea using affinity purified polyclonal antibody to GluR subunits (GluR 1-4). GluR 2/3 and GluR 4 immunoreactive (IR) staining was observed in rat spiral ganglion cells, while GluR 1 IR was not. GluR 4 IR staining was also seen in puncta at inner and outer hair cell bases. These results suggest that GluR 2/3 and GluR 4 are components of excitatory amino acid synapses in the rat cochlea.

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Year:  1994        PMID： 7896581     DOI： 10.1016/0378-5955(94)90114-7

Source DB:  PubMed          Journal:  Hear Res        ISSN： 0378-5955            Impact factor:   3.208


  12 in total

1.  Two modes of release shape the postsynaptic response at the inner hair cell ribbon synapse.

Authors:  Lisa Grant; Eunyoung Yi; Elisabeth Glowatzki
Journal:  J Neurosci       Date:  2010-03-24       Impact factor: 6.167

2.  Cobalt-Induced Ototoxicity in Rat Postnatal Cochlear Organotypic Cultures.

Authors:  Peng Li; Dalian Ding; Richard Salvi; Jerome A Roth
Journal:  Neurotox Res       Date:  2015-07-08       Impact factor: 3.911

Review 3.  Spiral ganglion neurones: an overview of morphology, firing behaviour, ionic channels and function.

Authors:  Zoltán Rusznák; Géza Szucs
Journal:  Pflugers Arch       Date:  2008-09-06       Impact factor: 3.657

4.  Organization of AMPA receptor subunits at a glutamate synapse: a quantitative immunogold analysis of hair cell synapses in the rat organ of Corti.

Authors:  A Matsubara; J H Laake; S Davanger; S Usami; O P Ottersen
Journal:  J Neurosci       Date:  1996-07-15       Impact factor: 6.167

5.  The glutamate receptor subunit delta1 is highly expressed in hair cells of the auditory and vestibular systems.

Authors:  S Safieddine; R J Wenthold
Journal:  J Neurosci       Date:  1997-10-01       Impact factor: 6.167

6.  Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear.

Authors:  Jeremy P Braude; Sarath Vijayakumar; Katherine Baumgarner; Rebecca Laurine; Timothy A Jones; Sherri M Jones; Sonja J Pyott
Journal:  Hear Res       Date:  2015-01-28       Impact factor: 3.208

7.  Persistence of Ca(v)1.3 Ca2+ channels in mature outer hair cells supports outer hair cell afferent signaling.

Authors:  Martina Knirsch; Niels Brandt; Claudia Braig; Stephanie Kuhn; Bernhard Hirt; Stefan Münkner; Marlies Knipper; Jutta Engel
Journal:  J Neurosci       Date:  2007-06-13       Impact factor: 6.167

Review 8.  [The role of cochlear neurotransmitters in tinnitus].

Authors:  B Mazurek; T Stöver; H Haupt; J Gross; A Szczepek
Journal:  HNO       Date:  2007-12       Impact factor: 1.284

Review 9.  Ototoxicity of Divalent Metals.

Authors:  Jerome A Roth; Richard Salvi
Journal:  Neurotox Res       Date:  2016-05-03       Impact factor: 3.911

10.  A corticotropin-releasing factor system expressed in the cochlea modulates hearing sensitivity and protects against noise-induced hearing loss.

Authors:  Christine E Graham; Johnvesly Basappa; Douglas E Vetter
Journal:  Neurobiol Dis       Date:  2010-01-28       Impact factor: 5.996
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