Literature DB >> 7896292

Isolation and genetic mapping of two novel members of the murine Wnt gene family, Wnt11 and Wnt12, and the mapping of Wnt5a and Wnt7a.

M C Adamson1, C Dennis, S Delaney, J Christiansen, S Monkley, C A Kozak, B Wainwright.   

Abstract

The murine Wnt genes are implicated in the control of a variety of developmental processes. Using a PCR-based approach, we have isolated two novel members of the murine Wnt gene family, Wnt11 and Wnt12. These cDNAs display an amino acid sequence identity of between 38 and 49% with all other murine Wnts over the regions that we have isolated. In addition, two previously described Wnt genes, Wnt5a and Wnt7a, were detected in RT-PCR products. Interspecific crosses were used to demonstrate close linkage between Wnt12 and Wnt1 on Chromosome (Chr) 15. Wnt7a was mapped to mouse Chr 6, Wnt5a to the centromeric region of Chr 14, and Wnt11 to Chr7.

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7896292     DOI： 10.1006/geno.1994.1575

Source DB:  PubMed          Journal:  Genomics        ISSN： 0888-7543            Impact factor:   5.736


  6 in total

1.  Analysis of 148 kb of genomic DNA around the wnt1 locus of Fugu rubripes.

Authors:  K Gellner; S Brenner
Journal:  Genome Res       Date:  1999-03       Impact factor: 9.043

2.  Genetic mapping of five mouse genes encoding synaptotagmins.

Authors:  O J Kwon; M C Adamson; H Chin; C A Kozak
Journal:  Mamm Genome       Date:  1995-12       Impact factor: 2.957

3.  Cerebellar deficient folia (cdf): a new mutation on mouse chromosome 6.

Authors:  S A Cook; R T Bronson; L R Donahue; N Ben-Arie; M T Davisson
Journal:  Mamm Genome       Date:  1997-02       Impact factor: 2.957

4.  Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice.

Authors:  F S Lee; T F Lane; A Kuo; G M Shackleford; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-14       Impact factor: 11.205

Review 5.  The Wnts.

Authors:  Jeffrey R Miller
Journal:  Genome Biol       Date:  2001-12-28       Impact factor: 13.583

6.  Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas.

Authors:  Fadzai Chinyengetere; David J Sekula; Yun Lu; Andrew J Giustini; Aarti Sanglikar; Masanori Kawakami; Tian Ma; Sandra S Burkett; Burton L Eisenberg; Wendy A Wells; Paul J Hoopes; Elizabeth G Demicco; Alexander J Lazar; Keila E Torres; Vincent Memoli; Sarah J Freemantle; Ethan Dmitrovsky
Journal:  BMC Cancer       Date:  2015-11-10       Impact factor: 4.430
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.