| Literature DB >> 7896286 |
B Kraus1, M Pohlschmidt, A L Leung, G G Germino, A Snarey, M C Schneider, S T Reeders, A M Frischauf.
Abstract
The major locus for autosomal dominant polycystic kidney disease (PKD1) is located in a gene-rich region on chromosome 16p13.3. Recently the identification of the gene responsible for PKD1 has been described. While searching for candidate genes in this region, we isolated a new member of the cyclin family. We have characterized the transcript by sequencing, determination of the exon intron boundaries, and Northern blot analysis. Cyclin F is related to A- and B-type cyclins by sequence, but its function is unknown.Entities:
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Year: 1994 PMID： 7896286 DOI： 10.1006/geno.1994.1578
Source DB: PubMed Journal: Genomics ISSN： 0888-7543 Impact factor: 5.736