Literature DB >> 7894499

Cloning and sequencing of a new non-functional CYP2D6 allele: deletion of T1795 in exon 3 generates a premature stop codon.

B Evert1, E U Griese, M Eichelbaum.   

Abstract

Entities:  

Mesh：

Substances：

Year:  1994        PMID： 7894499     DOI： 10.1097/00008571-199410000-00005

Source DB:  PubMed          Journal:  Pharmacogenetics        ISSN： 0960-314X


× No keyword cloud information.
  11 in total

1.  Identification of CYP2D6 impaired functional alleles in Mexican Americans.

Authors:  Huai-Rong Luo; Andrea Gaedigk; Vasileios Aloumanis; Yu-Jui Yvonne Wan
Journal:  Eur J Clin Pharmacol       Date:  2005-11-08       Impact factor: 2.953

Review 2.  Molecular basis of polymorphic drug metabolism.

Authors:  A K Daly
Journal:  J Mol Med (Berl)       Date:  1995-11       Impact factor: 4.599

3.  An additional allelic variant of the CYP2D6 gene causing impaired metabolism of sparteine.

Authors:  D Marez; M Legrand; N Sabbagh; J M Lo-Guidice; P Boone; F Broly
Journal:  Hum Genet       Date:  1996-05       Impact factor: 4.132

4.  Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

Authors:  C Sachse; J Brockmöller; S Bauer; I Roots
Journal:  Am J Hum Genet       Date:  1997-02       Impact factor: 11.025

5.  Role of cytochrome p450 isoenzymes 3A and 2D6 in the in vivo metabolism of mirabegron, a β3-adrenoceptor agonist.

Authors:  Jennifer Lee; Selina Moy; John Meijer; Walter Krauwinkel; Taiji Sawamoto; Virginie Kerbusch; Donna Kowalski; Michael Roy; Alan Marion; Shin Takusagawa; Marcel van Gelderen; James Keirns
Journal:  Clin Drug Investig       Date:  2013-06       Impact factor: 2.859

6.  Enantioselective pharmacokinetics of tramadol in CYP2D6 extensive and poor metabolizers.

Authors:  Rasmus Steen Pedersen; Per Damkier; Kim Brøsen
Journal:  Eur J Clin Pharmacol       Date:  2006-06-09       Impact factor: 2.953

7.  Steady-state plasma levels of nortriptyline and its 10-hydroxy metabolite: relationship to the CYP2D6 genotype.

Authors:  M L Dahl; L Bertilsson; C Nordin
Journal:  Psychopharmacology (Berl)       Date:  1996-02       Impact factor: 4.530

Review 8.  Cytochrome P450 2D6.

Authors:  Ryan P Owen; Katrin Sangkuhl; Teri E Klein; Russ B Altman
Journal:  Pharmacogenet Genomics       Date:  2009-07       Impact factor: 2.089

9.  The effect of mirabegron, a potent and selective β3-adrenoceptor agonist, on the pharmacokinetics of CYP2D6 substrates desipramine and metoprolol.

Authors:  Walter Krauwinkel; James Dickinson; Marloes Schaddelee; John Meijer; Reiner Tretter; Jeroen van de Wetering; Gregory Strabach; Marcel van Gelderen
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2013-06-01       Impact factor: 2.441

10.  Recommendations from the EGAPP Working Group: testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors.

Authors: 
Journal:  Genet Med       Date:  2007-12       Impact factor: 8.822
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.