| Literature DB >> 7894029 |
T Natazuka1, T Yamaguchi, T Murayama, M Fukase, T Matsui, T Isobe, K Chihara.
Abstract
A 35-year-old male presented with chronic myelomonocytic leukemia (CMMoL) after 6.5 years of alkylating agent therapy for IgG-kappa type multiple myeloma. The total dose of melphalan was 0.648 g. CMMoL was stable with weekly injection of alpha-interferon for one year. Thereafter, monocytosis and thrombocytopenia aggravated, and the patient died of disseminating intravascular coagulation. Prolonged drug therapy can induce CMMoL, as well as other myelodysplastic syndromes.Entities:
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Year: 1994 PMID： 7894029
Source DB: PubMed Journal: Int J Hematol ISSN： 0925-5710 Impact factor: 2.490