Literature DB >> 789241

Isolation of a low-molecular-weight antibacterial system from human amniotic fluid.

P Schlievert, W Johnson, R P Galask.   

Abstract

A low-molecular-weight antibacterial system has been isolated from human amniotic fluid. The bacterial inhibitor requires the metal cation zinc and a peptide with a molecular weight of 630. The peptide component was purified using ultrafiltration, gel filtration, and ion-exchange chromatography. It can be inactivated by digestion with carboxypeptidase. The amino acid composition of the peptide is: 3 glutamine-glutamic acid, 2 glycine, and 1 lysine. Removal of zinc from the peptide has been shown to remove bacterial inhibitory activity.

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Year:  1976        PMID： 789241      PMCID： PMC415508          DOI： 10.1128/iai.14.5.1156-1166.1976

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  32 in total

1.  DISC ELECTROPHORESIS. I. BACKGROUND AND THEORY.

Authors:  L ORNSTEIN
Journal:  Ann N Y Acad Sci       Date:  1964-12-28       Impact factor: 5.691

2.  Physical studies of lysozyme. I. Characterization.

Authors:  A J SOPHIANOPOULOS; C K RHODES; D N HOLCOMB; K E VAN HOLDE
Journal:  J Biol Chem       Date:  1962-04       Impact factor: 5.157

3.  An immunochemical study of the proteins of amniotic fluid and of maternal and foetal serum.

Authors:  M M DERRINGTON; J F SOOTHILL
Journal:  J Obstet Gynaecol Br Emp       Date:  1961-10

4.  A bactericidin for Bacillus subtilis in pregnancy.

Authors:  J P GUSDON
Journal:  J Immunol       Date:  1962-04       Impact factor: 5.422

5.  [The influence of manganese on the stability of lysozyme. II. The protective role of manganese during the hydrolysis of lysozyme by trypsin].

Authors:  L GORINI; F FELIX; C FROMAGEOT
Journal:  Biochim Biophys Acta       Date:  1953 Sep-Oct

6.  Disk electrophoresis of basic proteins and peptides on polyacrylamide gels.

Authors:  R A REISFELD; U J LEWIS; D E WILLIAMS
Journal:  Nature       Date:  1962-07-21       Impact factor: 49.962

7.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

8.  Spectroscopic determination of tryptophan and tyrosine in proteins.

Authors:  H Edelhoch
Journal:  Biochemistry       Date:  1967-07       Impact factor: 3.162

9.  Enhancement of bacterial growth in amniotic fluid by meconium.

Authors:  A L Florman; D Teubner
Journal:  J Pediatr       Date:  1969-01       Impact factor: 4.406

10.  Digestive activity of lysosomes. I. The digestion of proteins by extracts of rat liver lysosomes.

Authors:  J W Coffey; C De Duve
Journal:  J Biol Chem       Date:  1968-06-25       Impact factor: 5.157
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  12 in total

1.  Evidence that intra-amniotic infections are often the result of an ascending invasion - a molecular microbiological study.

Authors:  Roberto Romero; Nardhy Gomez-Lopez; Andrew D Winters; Eunjung Jung; Majid Shaman; Janine Bieda; Bogdan Panaitescu; Percy Pacora; Offer Erez; Jonathan M Greenberg; Madison M Ahmad; Chaur-Dong Hsu; Kevin R Theis
Journal:  J Perinat Med       Date:  2019-11-26       Impact factor: 1.901

2.  Pathogen or commensal?

Authors:  P A Davies
Journal:  Arch Dis Child       Date:  1980-03       Impact factor: 3.791

3.  The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies.

Authors:  Nardhy Gomez-Lopez; Roberto Romero; Yi Xu; Derek Miller; Yaozhu Leng; Bogdan Panaitescu; Pablo Silva; Jonathan Faro; Ali Alhousseini; Navleen Gill; Sonia S Hassan; Chaur-Dong Hsu
Journal:  Am J Reprod Immunol       Date:  2018-03-03       Impact factor: 3.886

4.  Molecular Dynamics Investigation into the Effect of Zinc(II) on the Structure and Membrane Interactions of the Antimicrobial Peptide Clavanin A.

Authors:  Searle S Duay; Gaurav Sharma; Rajeev Prabhakar; Alfredo M Angeles-Boza; Eric R May
Journal:  J Phys Chem B       Date:  2019-04-04       Impact factor: 2.991

5.  Effect of zinc and phosphate on an antibacterial peptide isolated from lung lavage.

Authors:  F M LaForce; D S Boose
Journal:  Infect Immun       Date:  1984-09       Impact factor: 3.441

6.  The interstitial lymphatic peritoneal mesothelium axis in portal hypertensive ascites: when in danger, go back to the sea.

Authors:  M A Aller; I Prieto; S Argudo; F de Vicente; L Santamaría; M P de Miguel; J L Arias; J Arias
Journal:  Int J Inflam       Date:  2010-10-05

7.  Isolation of an ovine pulmonary surfactant-associated anionic peptide bactericidal for Pasteurella haemolytica.

Authors:  K A Brogden; A J De Lucca; J Bland; S Elliott
Journal:  Proc Natl Acad Sci U S A       Date:  1996-01-09       Impact factor: 11.205

8.  Inhibitory effect of a copper-dipeptide complex on the establishment of a Clostridium perenne strain in the intestinal tract of gnotobiotic mice.

Authors:  F Dubos; J P Pelissier; C Andrieux; R Ducluzeau; P Raibaud
Journal:  Appl Environ Microbiol       Date:  1985-11       Impact factor: 4.792

9.  Enhancing effect of serum ultrafiltrate on the activity of cephalosporins against gram-negative bacilli.

Authors:  J E Leggett; W A Craig
Journal:  Antimicrob Agents Chemother       Date:  1989-01       Impact factor: 5.191

10.  Amniotic fluid activity against Bacteroides fragilis and group B streptococci.

Authors:  G Evaldson; C E Nord
Journal:  Med Microbiol Immunol       Date:  1981       Impact factor: 3.402
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