Literature DB >> 789219

[Clinical studies on Frubienzyme in a controlled double-blind trial].

I Raus.   

Abstract

In a controlled clinical trial Frubienzym (throat lozenges with 5 mg lysozyme, 2 mg papaine and 200 I.U. bacitracin) or placebo have been given to 100 patients with pharyngitis and/or tonsillitis for 4 days. Under treatment with Frubienzym reddening, swelling, matter and mucus in the throat, coughing, swelling and pain of lymphatic ganglions and pain of swallowing vanished more quickly than under placebo. The differences were significant (p less than 0,05, p less than 0,001 or even p less than 0,001; U-test of Wilcoxon, Man and Whitney). There were no side effects which could be attributed to Frubienzym.

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Year:  1976        PMID: 789219

Source DB:  PubMed          Journal:  Fortschr Med        ISSN: 0015-8178


  2 in total

1.  Efficacy of a benzocaine lozenge in the treatment of uncomplicated sore throat.

Authors:  Sigrun Chrubasik; Beate Beime; Florella Magora
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-10-21       Impact factor: 2.503

Review 2.  Topical (local) antibiotics for respiratory infections with sore throat: An antibiotic stewardship perspective.

Authors:  Sabiha Essack; John Bell; Douglas S Burgoyne; Martin Duerden; Adrian Shephard
Journal:  J Clin Pharm Ther       Date:  2019-08-13       Impact factor: 2.512

  2 in total

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