| Literature DB >> 7891838 |
K Ohkawa1, T Hirakawa-Sakurai, K Joh, T Asakura, K Takada, M Matsuda.
Abstract
Murine polyclonal antibody against purified bovine brain pyridoxal kinase (EC 2.7.1.35) was generated and showed cross-reactivity with rabbit brain pyridoxal kinase. This antibody was used to immunohistochemically examine the distribution of pyridoxal kinase in the rabbit brain. The cytoplasm of neuronal cells and neuroglial cells in the cerebral cortex, hippocampal region, brain nuclei and cerebellar cortex showed positive staining with various degrees of intensity. The neuronal cells and surrounding fibers in some brain nuclei, such as the area tegmentalis ventralis or the substantia nigra, showed intense staining. The neuronal cells of the hippocampal region showed somewhat weak reactivity, but some with intense reactivity were found sparsely distributed and positive staining fiber networks of a very low density were also observed.Entities:
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Year: 1994 PMID: 7891838 DOI: 10.1007/bf01006811
Source DB: PubMed Journal: Neurochem Res ISSN: 0364-3190 Impact factor: 3.996