Literature DB >> 7891488

Herpesvirus-like DNA sequences in patients with Mediterranean Kaposi's sarcoma.

N Dupin1, M Grandadam, V Calvez, I Gorin, J T Aubin, S Havard, F Lamy, M Leibowitch, J M Huraux, J P Escande.   

Abstract

DNA sequences closely related to herpesvirus-like sequences have been found in AIDS-associated Kaposi's sarcoma. Using PCR, we found herpesvirus-like DNA sequences in Kaposi's lesions and normal adjacent skin in five patients with Mediterranean Kaposi's sarcoma. We did not find these sequences in tissues from patients without Kaposi's sarcoma. Semi-quantitative PCR revealed many more herpesvirus-like sequences in Kaposi's lesions than in unaffected skin. Our results reinforce the hypothesis that an infectious agent closely related to gamma-herpesvirus is implicated in the pathogenesis of Mediterranean and AIDS-associated Kaposi's sarcoma.

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Year:  1995        PMID： 7891488     DOI： 10.1016/s0140-6736(95)90642-8

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  80 in total

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Authors:  Joseph G Sinkovics
Journal:  Pathol Oncol Res       Date:  1996       Impact factor: 3.201

2.  High-level variability in the ORF-K1 membrane protein gene at the left end of the Kaposi's sarcoma-associated herpesvirus genome defines four major virus subtypes and multiple variants or clades in different human populations.

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Journal:  J Virol       Date:  1999-05       Impact factor: 5.103

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Authors:  D K Braun; G Dominguez; P E Pellett
Journal:  Clin Microbiol Rev       Date:  1997-07       Impact factor: 26.132

4.  Comparison of serologic assays and PCR for diagnosis of human herpesvirus 8 infection.

Authors:  T J Spira; L Lam; S C Dollard; Y X Meng; C P Pau; J B Black; D Burns; B Cooper; M Hamid; J Huong; K Kite-Powell; P E Pellett
Journal:  J Clin Microbiol       Date:  2000-06       Impact factor: 5.948

5.  And then there were eight...

Authors:  S D Shafran; J M Conly
Journal:  Can J Infect Dis       Date:  1996-01

6.  Kaposi sarcoma presenting as dermal nodule.

Authors:  Kiran Alam; Veena Maheshwari; Manoranjan Varshney; Mehar Aziz; Mohammad Shahid; Mahfooz Basha; Kavita Gaur
Journal:  BMJ Case Rep       Date:  2011-04-19

Review 7.  Molecular biology of KSHV in relation to AIDS-associated oncogenesis.

Authors:  Whitney Greene; Kurt Kuhne; Fengchun Ye; Jiguo Chen; Fuchun Zhou; Xiufen Lei; Shou-Jiang Gao
Journal:  Cancer Treat Res       Date:  2007

8.  Herpes virus-like sequences are specifically found in Kaposi sarcoma lesions.

Authors:  E O'Neill; T H Henson; A J Ghorbani; M A Land; B L Webber; J V Garcia
Journal:  J Clin Pathol       Date:  1996-04       Impact factor: 3.411

9.  Absence of HHV-8 DNA sequences in malignant mesothelioma.

Authors:  V Ascoli; F Nardi; C Carnovale Scalzo; S Signoretti; A Pistilli; F Lo Coco
Journal:  Mol Pathol       Date:  1998-04

10.  High human herpesvirus 8 seroprevalence in the homosexual population in Switzerland.

Authors:  N Regamey; G Cathomas; M Schwager; M Wernli; T Harr; P Erb
Journal:  J Clin Microbiol       Date:  1998-06       Impact factor: 5.948
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