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Literature DB >> 7890430

Paracoccidioides brasiliensis-stimulated human gamma/delta T cells support antibody production by B cells.

M E Munk¹, R A Fazioli, V L Calich, S H Kaufmann.

Abstract

Paracoccidioidomycosis patients show hyperactive humoral immune responses. Consequently, we investigated whether cytokines in supernatants from Paracoccidioides brasiliensis-stimulated gamma/delta T cells support B-cell activation. We detected proliferation of B cells and increased immunoglobulin M (IgM) and IgG production. Thus, gamma/delta T cells may participate in polyclonal B-cell activation during paracoccidioidomycosis.

Entities: Disease Species

Mesh：

Substances：

Year: 1995 PMID： 7890430 PMCID： PMC173198 DOI： 10.1128/iai.63.4.1608-1610.1995

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

17 in total

1. Functionally distinct subsets of human gamma/delta T cells.

Authors: C T Morita; S Verma; P Aparicio; C Martinez; H Spits; M B Brenner
Journal: Eur J Immunol Date: 1991-12 Impact factor: 5.532

2. CD4-, CD8- gamma/delta cells from normal mice respond to a syngeneic B cell lymphoma and can induce its differentiation.

Authors: A I Sperling; H H Wortis
Journal: Int Immunol Date: 1989 Impact factor: 4.823

Review 3. Host-parasite relationships in paracoccidioidomycosis.

Authors: M Franco
Journal: J Med Vet Mycol Date: 1987-02

Review 4. Immune response to Paracoccidioides brasiliensis in human and animal hosts.

Authors: M Angela Restrepo
Journal: Curr Top Med Mycol Date: 1988

5. Circulating immune complexes and in vitro cell reactivity in paracoccidioidomycosis.

Authors: M Arango; F Oropeza; O Anderson; C Contreras; N Bianco; L Yarzábal
Journal: Mycopathologia Date: 1982-09-17 Impact factor: 2.574

6. Organization of immunoglobulin heavy chain genes and allelic deletion model.

Authors: T Honjo; T Kataoka
Journal: Proc Natl Acad Sci U S A Date: 1978-05 Impact factor: 11.205

7. Polyclonal B cell activation in paracoccidioidomycosis. Polyclonal activation in paracoccidioidomycosis.

Authors: D Chequer-Bou-Habib; C Daniel-Ribeiro; D M Banic; A C do Valle; B Galvao-Castro
Journal: Mycopathologia Date: 1989-11 Impact factor: 2.574

8. Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8- T helper cell lines that express the gamma delta T-cell antigen receptor.

Authors: S Rajagopalan; T Zordan; G C Tsokos; S K Datta
Journal: Proc Natl Acad Sci U S A Date: 1990-09 Impact factor: 11.205

Paracoccidioides brasiliensis-stimulated human gamma/delta T cells support antibody production by B cells.

1. Functionally distinct subsets of human gamma/delta T cells.

2. CD4-, CD8- gamma/delta cells from normal mice respond to a syngeneic B cell lymphoma and can induce its differentiation.

Review 3. Host-parasite relationships in paracoccidioidomycosis.

Review 4. Immune response to Paracoccidioides brasiliensis in human and animal hosts.

5. Circulating immune complexes and in vitro cell reactivity in paracoccidioidomycosis.

6. Organization of immunoglobulin heavy chain genes and allelic deletion model.

7. Polyclonal B cell activation in paracoccidioidomycosis. Polyclonal activation in paracoccidioidomycosis.

8. Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8- T helper cell lines that express the gamma delta T-cell antigen receptor.

9. Target cell lysis and IL-2 secretion by gamma/delta T lymphocytes after activation with bacteria.

10. Gamma delta T cells and the immune response in visceral leishmaniasis.

1. Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production.

2. T-cell Subsets and Antifungal Host Defenses.