Cytogenetics of astrocytomas.

Cytogenetic and molecular genetic analyses of all grades of human astrocytomas have provided interesting information on the mechanisms of their origin and malignant progression. Specific genetic events such as amplification and deletion are seemingly related to the stages of malignancy of astrocytic tumors. Genetic studies of human astroglial tumors can be significantly valuable as an additional tool in histopathology and in forecasting prognosis of patients.