Literature DB >> 7888760

Ancient origin of RNA editing in kinetoplastid protozoa.

L Simpson1, D A Maslov.   

Abstract

A rooted phylogenetic tree of the kinetoplastid protozoa has been constructed that, together with a comparative analysis of editing of several genes, leads to the surprising conclusion that extensive or pan-editing with multiple overlapping guide RNAs is more ancient than 5'-editing. The mechanism of editing is still uncertain, but multiple ribonucleoprotein complexes have been identified that contain components of the enzymatic machinery.

Mesh:

Substances:

Year:  1994        PMID: 7888760     DOI: 10.1016/0959-437x(94)90075-2

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN: 0959-437X            Impact factor:   5.578


  4 in total

Review 1.  A base called J.

Authors:  L Simpson
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-03       Impact factor: 11.205

2.  RNA editing in the free-living bodonid Bodo saltans.

Authors:  D Blom; A de Haan; M van den Berg; P Sloof; M Jirku; J Lukes; R Benne
Journal:  Nucleic Acids Res       Date:  1998-03-01       Impact factor: 16.971

3.  beta-D-glucosyl-hydroxymethyluracil is a conserved DNA modification in kinetoplastid protozoans and is abundant in their telomeres.

Authors:  F van Leeuwen; M C Taylor; A Mondragon; H Moreau; W Gibson; R Kieft; P Borst
Journal:  Proc Natl Acad Sci U S A       Date:  1998-03-03       Impact factor: 11.205

4.  Mitochondrial DNAs provide insight into trypanosome phylogeny and molecular evolution.

Authors:  C Kay; T A Williams; W Gibson
Journal:  BMC Evol Biol       Date:  2020-12-09       Impact factor: 3.260

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.