Literature DB >> 7888074

A signaling pathway governing early thymocyte maturation.

S J Anderson1, R M Perlmutter.   

Abstract

Recent evidence supports the view that p56lck, a non-receptor protein tyrosine kinase, serves as the signaling element that 'senses' synthesis of a functional T-cell receptor beta chain, thereby promoting thymocyte maturation. Here, Steven Anderson and Roger Perlmutter review current data, and outline the features of this developmental program.

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Year:  1995        PMID： 7888074     DOI： 10.1016/0167-5699(95)80096-4

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  17 in total

1.  CD3-epsilon overexpressed in prothymocytes acts as an oncogene.

Authors:  B Wang; J She; M Salio; D Allen; E Lacy; N Lonberg; C Terhorst
Journal:  Mol Med       Date:  1997-01       Impact factor: 6.354

2.  Real-time PCR method for the quantitative analysis of human T-cell receptor gamma and beta gene rearrangements.

Authors:  J L Chain; M L Joachims; S W Hooker; A B Laurent; C K Knott-Craig; L F Thompson
Journal:  J Immunol Methods       Date:  2005-03-18       Impact factor: 2.303

3.  Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsiveness.

Authors:  U Lorenz; K S Ravichandran; S J Burakoff; B G Neel
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-03       Impact factor: 11.205

4.  Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of Lck.

Authors:  Shi Niu; Haichun Xie; Eugene E Marcantonio
Journal:  Mol Biol Cell       Date:  2003-02       Impact factor: 4.138

5.  Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures.

Authors:  L F Thompson; C J Van de Wiele; A B Laurent; S W Hooker; J G Vaughn; H Jiang; K Khare; R E Kellems; M R Blackburn; M S Hershfield; R Resta
Journal:  J Clin Invest       Date:  2000-11       Impact factor: 14.808

Review 6.  SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels.

Authors:  Ulrike Lorenz
Journal:  Immunol Rev       Date:  2009-03       Impact factor: 12.988

7.  Replacement of pre-T cell receptor signaling functions by the CD4 coreceptor.

Authors:  A M Norment; K A Forbush; N Nguyen; M Malissen; R M Perlmutter
Journal:  J Exp Med       Date:  1997-01-06       Impact factor: 14.307

8.  The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit+ T cell progenitors and CD4/CD8 lineage decision in the thymus.

Authors:  Raif Yücel; Holger Karsunky; Ludger Klein-Hitpass; Tarik Möröy
Journal:  J Exp Med       Date:  2003-04-07       Impact factor: 14.307

9.  Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice.

Authors:  K E You-Ten; E S Muise; A Itié; E Michaliszyn; J Wagner; S Jothy; W S Lapp; M L Tremblay
Journal:  J Exp Med       Date:  1997-08-29       Impact factor: 14.307

10.  Network rewiring is an important mechanism of gene essentiality change.

Authors:  Jinho Kim; Inhae Kim; Seong Kyu Han; James U Bowie; Sanguk Kim
Journal:  Sci Rep       Date:  2012-11-29       Impact factor: 4.379
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