OBJECTIVE: To describe the current indications and operative outcomes of pancreatic resection. DESIGN: Retrospective case series. SETTING: Referral practice in a university hospital. PATIENTS: Two hundred thirty-one consecutive patients undergoing pancreatoduodenectomy (PD), distal pancreatectomy (DP), or total pancreatectomy (TP) over a 44-month period. Their ages ranged from 16 to 85 years, with a mean of 54 years; 20% of the patients were 70 years old or older. MAIN OUTCOME MEASURES: Mortality, complications, and length of hospital stay. RESULTS: Operative mortality was 0.4% (one death following DP); there were no deaths in 142 PDs or in 18 TPs. The most common complication following PD was delayed gastric emptying. Pancreatic fistula occurred in 6.3% of PD and in 9.8% of DP patients. Overall, 58% of PD, 80% of DP, and 78% of TP patients had no complications. The mean +/- SD length of hospital stay was 15 +/- 7, 10 +/- 5, and 15 +/- 6 days for PD, DP, and TP, respectively. Reoperation for any cause was necessary in only 1.2% (3/231). The most frequent indication for PD was pancreatic cancer (36%) followed by chronic pancreatitis (26%); for DP it was chronic pancreatitis (28%) and cystic neoplasms (27%); and for TP, chronic pancreatitis (55%). Newer indications for pancreatic resection included mucinous ductal ectasia and intraductal papillary tumors (eight cases, 4%) and metastatic tumors (eight cases, 4%). CONCLUSIONS: Current indications for pancreatic resection have expanded. These procedures are associated with a low risk for death and postoperative complications when performed in a high-volume setting.
OBJECTIVE: To describe the current indications and operative outcomes of pancreatic resection. DESIGN: Retrospective case series. SETTING: Referral practice in a university hospital. PATIENTS: Two hundred thirty-one consecutive patients undergoing pancreatoduodenectomy (PD), distal pancreatectomy (DP), or total pancreatectomy (TP) over a 44-month period. Their ages ranged from 16 to 85 years, with a mean of 54 years; 20% of the patients were 70 years old or older. MAIN OUTCOME MEASURES: Mortality, complications, and length of hospital stay. RESULTS: Operative mortality was 0.4% (one death following DP); there were no deaths in 142 PDs or in 18 TPs. The most common complication following PD was delayed gastric emptying. Pancreatic fistula occurred in 6.3% of PD and in 9.8% of DPpatients. Overall, 58% of PD, 80% of DP, and 78% of TPpatients had no complications. The mean +/- SD length of hospital stay was 15 +/- 7, 10 +/- 5, and 15 +/- 6 days for PD, DP, and TP, respectively. Reoperation for any cause was necessary in only 1.2% (3/231). The most frequent indication for PD was pancreatic cancer (36%) followed by chronic pancreatitis (26%); for DP it was chronic pancreatitis (28%) and cystic neoplasms (27%); and for TP, chronic pancreatitis (55%). Newer indications for pancreatic resection included mucinous ductal ectasia and intraductal papillary tumors (eight cases, 4%) and metastatic tumors (eight cases, 4%). CONCLUSIONS: Current indications for pancreatic resection have expanded. These procedures are associated with a low risk for death and postoperative complications when performed in a high-volume setting.
Authors: Shu You Peng; Yi Ping Mou; Yin Bin Liu; Ying Su; Cheng Hong Peng; Xiu Jun Cai; Yu Lian Wu; Lin Hua Zhou Journal: J Gastrointest Surg Date: 2003-11 Impact factor: 3.452
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Authors: Marco Pericoli Ridolfini; Sergio Alfieri; Stavros Gourgiotis; Dario Di Miceli; Fabio Rotondi; Giuseppe Quero; Roberta Manghi; Giovanni Battista Doglietto Journal: World J Gastroenterol Date: 2007-10-14 Impact factor: 5.742