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Literature DB >> 788758

The effect on blood pressure of beta-adrenoceptor blocking drugs administered once daily and their duration of action when therapy is ceased.

Abstract

The control of blood pressure achieved was similar whether pindolol or propranolol was given once or three times daily. When the drugs were ceased the antihypertensive effect lasted for longer than 24 h. There was no rebound hypertension. The full effect of the drug on blood pressure was seen within 24 h of its recommencement. Changes in blood pressure, pulse rate, and plasma renin activity occurred but these were not considered to be causally related. The response of plasma renin activity to posture was ablated when the patients were receiving beta-adrenoceptor blocking drugs.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Propranolol
Pindolol
Renin

Year: 1976 PMID： 788758 PMCID： PMC1428952 DOI： 10.1111/j.1365-2125.1976.tb00638.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

5 in total

1. Hypertension--1974.

Authors: J N Cohn
Journal: Arch Intern Med Date: 1974-06

2. Blood pressure crisis following withdrawal of clonidine (Catapres, Catapresan), with special reference to arterial and urinary catecholamine levels, and suggestions for acute management.

Authors: L Hansson; S N Hunyor; S Julius; S W Hoobler
Journal: Am Heart J Date: 1973-05 Impact factor: 4.749

3. Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases.

Authors: F R Bühler; J H Laragh; L Baer; E D Vaughan; H R Brunner
Journal: N Engl J Med Date: 1972-12-14 Impact factor: 91.245

4. Beta-adrenergic receptor blocking drugs, hypertension and plasma renin.

Authors: T O Morgan; R Roberts; S L Carney; W J Louis; A E Doyle
Journal: Br J Clin Pharmacol Date: 1975-04 Impact factor: 4.335

5. Treatment of hypertension with propranolol.

Authors: B N Prichard; P M Gillam
Journal: Br Med J Date: 1969-01-04

5 in total

24 in total

Review 1. The second Lilly Prize Lecture, University of Newcastle, July 1977. beta-Adrenergic receptor blockade in hypertension, past, present and future.

Authors: B N Prichard
Journal: Br J Clin Pharmacol Date: 1978-05 Impact factor: 4.335

Review 2. Treating hypertension. The place of beta blockade.

Authors: D W Barritt; A J Marshall
Journal: Br Heart J Date: 1977-08

3. Adrenoceptor blocking drugs: clinical pharmacology and therapeutic use.

Authors: D G McDevitt
Journal: Drugs Date: 1979-04 Impact factor: 9.546

4. Comparison between atenolol and nadolol in essential hypertension at rest and on exercise.

Authors: R G Wilcox; J R Hampton
Journal: Br J Clin Pharmacol Date: 1982-06 Impact factor: 4.335

5. Observation on the efficacy and pharmacokinetics of betaxolol (SL 75212), a cardioselective beta-adrenoceptor blocking drug.

Authors: K Balnave; J D Neill; C J Russell; D W Harron; W J Leahey; R Wilson; R G Shanks
Journal: Br J Clin Pharmacol Date: 1981-02 Impact factor: 4.335

The effect on blood pressure of beta-adrenoceptor blocking drugs administered once daily and their duration of action when therapy is ceased.

1. Hypertension--1974.

2. Blood pressure crisis following withdrawal of clonidine (Catapres, Catapresan), with special reference to arterial and urinary catecholamine levels, and suggestions for acute management.

3. Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypertensive diseases.

4. Beta-adrenergic receptor blocking drugs, hypertension and plasma renin.

5. Treatment of hypertension with propranolol.

Review 1. The second Lilly Prize Lecture, University of Newcastle, July 1977. beta-Adrenergic receptor blockade in hypertension, past, present and future.

Review 2. Treating hypertension. The place of beta blockade.

3. Adrenoceptor blocking drugs: clinical pharmacology and therapeutic use.

4. Comparison between atenolol and nadolol in essential hypertension at rest and on exercise.

5. Observation on the efficacy and pharmacokinetics of betaxolol (SL 75212), a cardioselective beta-adrenoceptor blocking drug.

6. Comparative study of atenolol, metoprolol, metoprolol durules, and slow-release oxprenolol in essential hypertension.

7. Comparison of once and twice daily administration of sotalol in the treatment of hypertension.

8. Acebutolol in hypertension--double-blind trial against placebo.

Review 9. Pharmacokinetics of long acting propranolol. Implications for therapeutic use.

10. Nontraditional problems of antihypertensive management.