Literature DB >> 788748

How double blind is double blind? And does it matter?

E C Huskisson, J Scott.   

Abstract

In an apparently double blind crossover study, two experienced measurement technicians were able to identify many of the treatment periods. They most often correctly identified aspirin, a drug with prominent effects and side effects. It is argued that in many circumstances it is better to use a blind observer who is not concerned with the giving of treatment or the collection of side effects.

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Year:  1976        PMID: 788748      PMCID: PMC1428878          DOI: 10.1111/j.1365-2125.1976.tb00612.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  3 in total

1.  Placebos in the treatment of rheumatoid arthritis and other rheumatic conditions.

Authors:  E F TRAUT; E W PASSARELLI
Journal:  Ann Rheum Dis       Date:  1957-03       Impact factor: 19.103

2.  Simple analgesics for arthritis.

Authors:  E C Huskisson
Journal:  Br Med J       Date:  1974-10-26

3.  Comparison of azathioprine, cyclophosphamide, and gold in treatment of rheumatoid arthritis.

Authors:  H L Currey; J Harris; R M Mason; J Woodland; T Beveridge; C J Roberts; D W Vere; A S Dixon; J Davies; B Owen-Smith
Journal:  Br Med J       Date:  1974-09-28
  3 in total
  3 in total

Review 1.  Hydrotherapy, balneotherapy, and spa treatment in pain management.

Authors:  Tamás Bender; Zeki Karagülle; Géza P Bálint; Christoph Gutenbrunner; Péter V Bálint; Shaul Sukenik
Journal:  Rheumatol Int       Date:  2004-07-15       Impact factor: 2.631

2.  Quality of reports of clinical trials submitted by the drug industry to the Finnish and Swedish control authorities.

Authors:  E Hemminki
Journal:  Eur J Clin Pharmacol       Date:  1981-02       Impact factor: 2.953

3.  Establishing mild, moderate, and severe scores for cancer-related symptoms: how consistent and clinically meaningful are interference-based severity cut-points?

Authors:  Barbara Given; Charles W Given; Alla Sikorskii; Sangchoon Jeon; Ruth McCorkle; Victoria Champion; David Decker
Journal:  J Pain Symptom Manage       Date:  2007-12-26       Impact factor: 3.612

  3 in total

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