Literature DB >> 7886907

Major antigens of Cryptosporidium parvum recognised by serum antibodies from different infected animal species and man.

J M Répérant1, M Naciri, S Iochmann, M Tilley, D T Bout.   

Abstract

Serum humoral immune response to Cryptosporidium parvum was evaluated in six species: mouse, rabbit, lamb, calf, pig and man. Electrophoretic and immunoblot analysis showed that specific animal antibody response appeared between Day 4 and Day 15 post inoculation. The two main target antigens had apparent molecular weights of 15-17 and 23 kDa. They were recognised by each species studied. Serum IgA intensively recognised the 15-17 kDa antigen, except in rabbit. This study demonstrates that these two antigens are consistent targets of humoral immune response and can therefore be of great interest in studies of therapy/prophylaxis.

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Year:  1994        PMID： 7886907     DOI： 10.1016/0304-4017(94)90051-5

Source DB:  PubMed          Journal:  Vet Parasitol        ISSN： 0304-4017            Impact factor:   2.738


  18 in total

1.  Infection with Cryptosporidium hominis provides incomplete protection of the host against Cryptosporidium parvum.

Authors:  Abhineet Sheoran; Anthony Wiffin; Giovanni Widmer; Pradeep Singh; Saul Tzipori
Journal:  J Infect Dis       Date:  2012-01-25       Impact factor: 5.226

2.  Detection by enzyme immunoassay of serum immunoglobulin G antibodies that recognize specific Cryptosporidium parvum antigens.

Authors:  J W Priest; J P Kwon; D M Moss; J M Roberts; M J Arrowood; M S Dworkin; D D Juranek; P J Lammie
Journal:  J Clin Microbiol       Date:  1999-05       Impact factor: 5.948

Review 3.  Intestinal immune response to human Cryptosporidium sp. infection.

Authors:  Birte Pantenburg; Sara M Dann; Heuy-Ching Wang; Prema Robinson; Alejandro Castellanos-Gonzalez; Dorothy E Lewis; A Clinton White
Journal:  Infect Immun       Date:  2007-10-29       Impact factor: 3.441

Review 4.  Natural pathogens of laboratory mice, rats, and rabbits and their effects on research.

Authors:  D G Baker
Journal:  Clin Microbiol Rev       Date:  1998-04       Impact factor: 26.132

5.  Antibody responses to the immunodominant Cryptosporidium gp15 antigen and gp15 polymorphisms in a case-control study of cryptosporidiosis in children in Bangladesh.

Authors:  Genève M Allison; Kathleen A Rogers; Anoli Borad; Sabeena Ahmed; Mohammad Mahbubul Karim; Anne V Kane; Patricia L Hibberd; Elena N Naumova; Stephen B Calderwood; Edward T Ryan; Wasif A Khan; Honorine D Ward
Journal:  Am J Trop Med Hyg       Date:  2011-07       Impact factor: 2.345

6.  Enzyme immunoassay detection of antigen-specific immunoglobulin g antibodies in longitudinal serum samples from patients with cryptosporidiosis.

Authors:  J W Priest; A Li; M Khan; M J Arrowood; P J Lammie; C S Ong; J M Roberts; J Isaac-Renton
Journal:  Clin Diagn Lab Immunol       Date:  2001-03

Review 7.  Challenges in understanding the immunopathogenesis of Cryptosporidium infections in humans.

Authors:  R J Kothavade
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2011-04-12       Impact factor: 3.267

8.  Cloning and sequence analysis of a highly polymorphic Cryptosporidium parvum gene encoding a 60-kilodalton glycoprotein and characterization of its 15- and 45-kilodalton zoite surface antigen products.

Authors:  W B Strong; J Gut; R G Nelson
Journal:  Infect Immun       Date:  2000-07       Impact factor: 3.441

9.  Recombinant Cryptosporidium parvum p23 as a target for the detection of Cryptosporidium-specific antibody in calf sera.

Authors:  Parviz Shayan; Elahe Ebrahimzadeh; Mohamad-Reaza Mokhber-Dezfouli; Sadegh Rahbari
Journal:  Parasitol Res       Date:  2008-08-03       Impact factor: 2.289

10.  Induction of murine immune responses by DNA encoding a 23-kDa antigen of Cryptosporidium parvum.

Authors:  Humphrey N Ehigiator; Pablo Romagnoli; Jeffrey W Priest; W Evan Secor; Jan R Mead
Journal:  Parasitol Res       Date:  2007-05-09       Impact factor: 2.289
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