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Literature DB >> 7883746

Computer prediction of general PCR products based on dynamical solution structures of DNA.

Abstract

A computer program which can predict general PCR products was developed and experimentally verified to be useful. This means that the approximation of solution structures of DNA based solely on Watson-Crick base pairing is effective. Intramolecular higher structures were shown to be responsible for the discrepancies between the predictions and the experimental results. This study provides a theoretical background to arbitrarily primed (or random) PCR. Other basic issues relating to general PCR are also discussed.

Mesh：

Substances：
Solutions
DNA

Year: 1994 PMID： 7883746 DOI： 10.1093/oxfordjournals.jbchem.a124589

Source DB: PubMed Journal: J Biochem ISSN： 0021-924X Impact factor: 3.387

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Cited

8 in total

1. Whole genome sequence-enabled prediction of sequences performed for random PCR products of Escherichia coli.

Authors: K Nishigaki; A Saito; H Takashi; M Naimuddin
Journal: Nucleic Acids Res Date: 2000-05-01 Impact factor: 16.971

2. A mathematical model and a computerized simulation of PCR using complex templates.

Authors: E Rubin; A A Levy
Journal: Nucleic Acids Res Date: 1996-09-15 Impact factor: 16.971

3. Genome profiling (GP) method based classification of insects: congruence with that of classical phenotype-based one.

Authors: Shamim Ahmed; Manabu Komori; Sachika Tsuji-Ueno; Miho Suzuki; Akinori Kosaku; Kiyoshi Miyamoto; Koichi Nishigaki
Journal: PLoS One Date: 2011-08-31 Impact factor: 3.240

4. Establishment of a reborn MMV-microarray technology: realization of microbiome analysis and other hitherto inaccessible technologies.

Authors: Harshita Sharma; Yasunori Kinoshita; Seiichi Fujiu; Shota Nomura; Mizuho Sawada; Shamim Ahmed; Masaki Shibuya; Kosaku Shirai; Syota Takamatsu; Tsuyoshi Watanabe; Hitoshi Yamazaki; Ryohei Kamiyama; Tetsuya Kobayashi; Hidenao Arai; Miho Suzuki; Naoto Nemoto; Ki Ando; Hidekazu Uchida; Koichiro Kitamura; Osamu Takei; Koichi Nishigaki
Journal: BMC Biotechnol Date: 2014-08-21 Impact factor: 2.563

5. The genome profiling method can be applied for species identification of biological materials collected at crime scenes.

Authors: Takako Kinebuchi; Nozomi Idota; Hajime Tsuboi; Marin Takaso; Risa Bando; Hiroshi Ikegaya
Journal: BMC Genet Date: 2019-06-10 Impact factor: 2.797

Computer prediction of general PCR products based on dynamical solution structures of DNA.

1. Whole genome sequence-enabled prediction of sequences performed for random PCR products of Escherichia coli.

2. A mathematical model and a computerized simulation of PCR using complex templates.

3. Genome profiling (GP) method based classification of insects: congruence with that of classical phenotype-based one.

4. Establishment of a reborn MMV-microarray technology: realization of microbiome analysis and other hitherto inaccessible technologies.

5. The genome profiling method can be applied for species identification of biological materials collected at crime scenes.

6. A solution for universal classification of species based on genomic DNA.

7. Systematic genome sequence differences among leaf cells within individual trees.

8. Familial clustering of mice consistent to known pedigrees enabled by the genome profiling (GP) method.