Endogenous opioid peptide level changes under electrostimulation and their assessment by the EEG.

Endogenous opioid peptide (EOP) system plays an important role in the interaction of human organism with different stress factors, providing stress-limiting and stress-protective functions. Different kinds of electrostimulation seem to produce anti-stress and pain relief effects due to EOP system activation. The presented paper reviews recent literature concerning EOP system activation under electrostimulation and its reflections in the EEG characteristics. The results and opportunities of high resolution EEG structure analysis utilization for EOP level control, as well as for stress-induced state assessment and correction via resonance activation of brain EEG oscillators by means of frequency-tuned external stimulation are presented.