| Literature DB >> 7880855 |
H Okada1, K Ishii, K Nunoki, N Taira.
Abstract
Recently, pIcln has been reported to be a regulator of a swelling-induced chloride conductance. We have cloned a cDNA RCL-H1 from rabbit heart, of which primary structure is highly homologous to that of pIcln. Outwardly rectifying currents were recorded in oocytes expressing RCL-H1, which is consistent with the result of pIcln. RNA blot analysis revealed the widespread expression of RCL-H1 mRNA in rabbit tissues. RCL-H1 may play an important role in regulating cell volume and give a clue to revealing molecular structure of swelling-induced chloride channel(s).Entities:
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Year: 1995 PMID： 7880855 DOI： 10.1016/0005-2736(95)00015-u
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002