Literature DB >> 7877021

Intrapleural instillation of urokinase in the treatment of loculated pleural effusions in children.

G Stringel1, A R Hartman.   

Abstract

The authors report on the use of intrapleural instillation of urokinase in the treatment of loculated pleural effusions in two pediatric patients. Urokinase helps to lyse fibrin by converting plasminogen to plasmin. The intrapleural instillation of urokinase is safe and effective for promoting drainage of loculated intrapleural effusions, and it proved a useful option in the treatment of persistent loculations.

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Year:  1994        PMID： 7877021     DOI： 10.1016/0022-3468(94)90209-7

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN： 0022-3468            Impact factor:   2.545


  7 in total

1.  BTS guidelines for the management of pleural infection in children.

Authors:  I M Balfour-Lynn; E Abrahamson; G Cohen; J Hartley; S King; D Parikh; D Spencer; A H Thomson; D Urquhart
Journal:  Thorax       Date:  2005-02       Impact factor: 9.139

2.  Retrospective analysis of large-dose intrapleural alteplase for complicated pediatric parapneumonic effusion and empyema.

Authors:  Jessica L Taylor; Meixia Liu; David S Hoff
Journal:  J Pediatr Pharmacol Ther       Date:  2015 Mar-Apr

3.  Randomised trial of intrapleural urokinase in the treatment of childhood empyema.

Authors:  A H Thomson; J Hull; M R Kumar; C Wallis; I M Balfour Lynn
Journal:  Thorax       Date:  2002-04       Impact factor: 9.139

4.  The time course of resolution of adhesions during fibrinolytic therapy in tetracycline-induced pleural injury in rabbits.

Authors:  Andrey A Komissarov; Galina Florova; Ali O Azghani; Ann Buchanan; William M Bradley; Chris Schaefer; Kathleen Koenig; Steven Idell
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2015-07-10       Impact factor: 5.464

5.  Thoracoscopic decortication vs tube thoracostomy with fibrinolysis for empyema in children: a prospective, randomized trial.

Authors:  Shawn D St Peter; Kuojen Tsao; Troy L Spilde; Scott J Keckler; Christopher Harrison; Mary Ann Jackson; Susan W Sharp; Walter S Andrews; Doug C Rivard; Frank P Morello; George W Holcomb; Daniel J Ostlie
Journal:  J Pediatr Surg       Date:  2009-01       Impact factor: 2.545

6.  Intrapleural therapy in management of complicated parapneumonic effusions and empyema.

Authors:  Alaeldin H Ahmed; Tariq E Yacoub
Journal:  Clin Pharmacol       Date:  2010-11-22

7.  Video-assisted thoracoscopic surgery in the management of pediatric empyema.

Authors:  R R Gandhi; G Stringel
Journal:  JSLS       Date:  1997 Jul-Sep       Impact factor: 2.172
  7 in total

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