| Literature DB >> 7876618 |
O A Anzala1, N J Nagelkerke, J J Bwayo, D Holton, S Moses, E N Ngugi, J O Ndinya-Achola, F A Plummer.
Abstract
From a cohort of female sex workers in Nairobi, Kenya, 163 women were observed to seroconvert to human immunodeficiency virus type 1 (HIV-1) and followed to study progression to HIV-1-related disease. The effect of several covariables on disease progression was studied using a Weibull proportional hazards model. The Weibull survival model was fitted to the observed incubation times. Estimates of the median duration to CDC stage IV-A and IV-C disease were 3.5 and 4.4 years, respectively. Condom use before seroconversion was associated with a reduced risk of CDC stage IV-A disease (relative risk = .64, P < .05). The incubation time of HIV-1-related disease is extremely short in this population.Entities:
Mesh：
Year: 1995 PMID： 7876618 DOI： 10.1093/infdis/171.3.686
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226