AIMS: To evaluate the efficacy of transforming growth factor beta (TGF-beta) for the prognosis of pulmonary adenocarcinoma. METHODS: TGF-beta was detected immunohistochemically using the avidin-biotin-peroxidase complex technique in resected pulmonary adenocarcinomas from 88 patients. RESULTS: Of the 88 patients, 39 were TGF-beta negative and 45 TGF-beta positive. The five year survival rate was 56% for the TGF-beta negative and 16% for the TGF-beta positive group. CONCLUSIONS: TGF-beta can be used as a prognostic factor in pulmonary adenocarcinoma.
AIMS: To evaluate the efficacy of transforming growth factor beta (TGF-beta) for the prognosis of pulmonary adenocarcinoma. METHODS:TGF-beta was detected immunohistochemically using the avidin-biotin-peroxidase complex technique in resected pulmonary adenocarcinomas from 88 patients. RESULTS: Of the 88 patients, 39 were TGF-beta negative and 45 TGF-beta positive. The five year survival rate was 56% for the TGF-beta negative and 16% for the TGF-beta positive group. CONCLUSIONS:TGF-beta can be used as a prognostic factor in pulmonary adenocarcinoma.
Authors: Dong Park; Hee Jung Son; Sang Yong Song; Won Hyeok Choe; Yun Jeong Lim; Sang Jong Park; Jae J Kim; Young Ho Kim; Poong Lyul Rhee; Seung Woon Paik; Jong Chul Rhee; Kyoo Wan Choi Journal: Korean J Intern Med Date: 2002-09 Impact factor: 2.884