Literature DB >> 7875959

Proton magnetic resonance spectroscopy in patients with ischemic stroke.

F Federico1, C Conte, I L Simone, P Giannini, M Liguori, E Picciola, C Tortorella, E Ferrari.   

Abstract

Proton magnetic resonance spectroscopy (1H-MRS) is a non-invasive technique which has proved to be useful for monitoring various brain metabolites (N-acetyl-aspartate, choline, creatine-phosphocreatine, lactate). A total of 18 patients underwent a combined magnetic resonance imaging (MRI)/1H-MRS protocol in order to evaluate the distribution of the metabolites in the various stages of cerebral ischemia. Our results show a marked decrease of N-acetyl-aspartate and a large content of Lactate during the early phases, and a decrease in N-acetyl-aspartate, choline and creatine-phosphocreatine (Cr-PCr) during the chronic phase.

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Year:  1994        PMID： 7875959     DOI： 10.1007/bf02339905

Source DB:  PubMed          Journal:  Ital J Neurol Sci        ISSN： 0392-0461


  10 in total

1.  Localized high-resolution proton NMR spectroscopy using stimulated echoes: initial applications to human brain in vivo.

Authors:  J Frahm; H Bruhn; M L Gyngell; K D Merboldt; W Hänicke; R Sauter
Journal:  Magn Reson Med       Date:  1989-01       Impact factor: 4.668

2.  Human brain infarction: proton MR spectroscopy.

Authors:  J H Duijn; G B Matson; A A Maudsley; J W Hugg; M W Weiner
Journal:  Radiology       Date:  1992-06       Impact factor: 11.105

3.  Longitudinal changes in proton magnetic resonance spectroscopy in cerebral infarction.

Authors:  K Houkin; K Kamada; H Kamiyama; Y Iwasaki; H Abe; T Kashiwaba
Journal:  Stroke       Date:  1993-09       Impact factor: 7.914

4.  Combined magnetic resonance imaging and proton magnetic resonance spectroscopy of patients with acute stroke.

Authors:  S R Felber; F T Aichner; R Sauter; F Gerstenbrand
Journal:  Stroke       Date:  1992-08       Impact factor: 7.914

5.  Spectroscopic imaging of stroke in humans: histopathology correlates of spectral changes.

Authors:  O A Petroff; G D Graham; A M Blamire; M al-Rayess; D L Rothman; P B Fayad; L M Brass; R G Shulman; J W Prichard
Journal:  Neurology       Date:  1992-07       Impact factor: 9.910

6.  Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients.

Authors:  G D Graham; A M Blamire; A M Howseman; D L Rothman; P B Fayad; L M Brass; O A Petroff; R G Shulman; J W Prichard
Journal:  Stroke       Date:  1992-03       Impact factor: 7.914

7.  Localized proton NMR spectroscopy in different regions of the human brain in vivo. Relaxation times and concentrations of cerebral metabolites.

Authors:  J Frahm; H Bruhn; M L Gyngell; K D Merboldt; W Hänicke; R Sauter
Journal:  Magn Reson Med       Date:  1989-07       Impact factor: 4.668

8.  Elevated lactate and alkalosis in chronic human brain infarction observed by 1H and 31P MR spectroscopic imaging.

Authors:  J W Hugg; J H Duijn; G B Matson; A A Maudsley; J S Tsuruda; D F Gelinas; M W Weiner
Journal:  J Cereb Blood Flow Metab       Date:  1992-09       Impact factor: 6.200

9.  Cerebral lactate detected by regional proton magnetic resonance spectroscopy in a patient with cerebral infarction.

Authors:  J W Berkelbach van der Sprenkel; P R Luyten; P C van Rijen; C A Tulleken; J A den Hollander
Journal:  Stroke       Date:  1988-12       Impact factor: 7.914

10.  Early time course of N-acetylaspartate, creatine and phosphocreatine, and compounds containing choline in the brain after acute stroke. A proton magnetic resonance spectroscopy study.

Authors:  P Gideon; O Henriksen; B Sperling; P Christiansen; T S Olsen; H S Jørgensen; P Arlien-Søborg
Journal:  Stroke       Date:  1992-11       Impact factor: 7.914
  10 in total
  3 in total

1.  Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology.

Authors:  Dikoma C Shungu; Nora Weiduschat; James W Murrough; Xiangling Mao; Sarah Pillemer; Jonathan P Dyke; Marvin S Medow; Benjamin H Natelson; Julian M Stewart; Sanjay J Mathew
Journal:  NMR Biomed       Date:  2012-01-27       Impact factor: 4.044

2.  Prognostic significance of metabolic changes detected by proton magnetic resonance spectroscopy in ischaemic stroke.

Authors:  F Federico; I L Simone; C Conte; V Lucivero; P Giannini; M Liguori; E Picciola; C Tortorella
Journal:  J Neurol       Date:  1996-03       Impact factor: 4.849

3.  Magnetic resonance lactate and lipid signals in rat brain after middle cerebral artery occlusion model.

Authors:  Kuniaki Harada; Osamu Honmou; He Liu; Michio Bando; Kiyohiro Houkin; Jeffery D Kocsis
Journal:  Brain Res       Date:  2006-12-29       Impact factor: 3.252
  3 in total

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