| Literature DB >> 7875536 |
A F Rump1, M Schüssler, D Acar, A Cordes, M Theisohn, R Rösen, W Klaus, U Fricke.
Abstract
1. The functional effects of the flavonoid luteolin-7-glucoside (LUT) were investigated in Langendorff-rabbit hearts perfused at constant pressure. Repetitive myocardial ischemia was induced by coronary artery ligature and quantified from NADH-fluorescence photography. 2. LUT significantly enhanced left ventricular pressure and the global and relative coronary flow (= global coronary flow/pressure-rate product). 3. LUT significantly diminished epicardial NADH-fluorescence area and intensity. 4. LUT is an inodilator possessing cardioprotective properties. These might be related to an improvement of myocardial perfusion and/or to free radical scavenging properties.Entities:
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Year: 1994 PMID： 7875536 DOI： 10.1016/0306-3623(94)90129-5
Source DB: PubMed Journal: Gen Pharmacol ISSN： 0306-3623