| Literature DB >> 7873613 |
K Kosuga1, S Hata, T Osumi, J Sakakibara, T Ono.
Abstract
A full-length cDNA encoding mouse squalene epoxidase was isolated by screening a mouse liver cDNA library with the rat squalene epoxidase gene as a probe. The cDNA had an open reading frame for a 572 amino acid polypeptide with a calculated molecular mass of 63.8 kDa. The predicted amino acid sequence of the mouse enzyme contained an FAD-binding motif, and was 93% identical to that of the rat enzyme. The former is one amino acid shorter than the latter. Blotting analyses showed that the mRNA is 2.8 kb in size and that a single copy of the gene is present in the mouse genome.Entities:
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Year: 1995 PMID： 7873613 DOI： 10.1016/0167-4781(94)00245-x
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002