Literature DB >> 7871593

GAPs for rho-related GTPases.

N Lamarche1, A Hall.   

Abstract

Ras-related GTP-binding proteins (GTPases) of the rho subfamily play important roles in regulating the organization of the actin cytoskeleton. A large number of multifunctional proteins that can stimulate their intrinsic GTPase activity have been identified. Here, we discuss the nature of such GTPase-activating proteins (GAPs) and their potential importance for cell signalling.

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Year:  1994        PMID： 7871593     DOI： 10.1016/0168-9525(94)90114-7

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  63 in total

Review 1.  Rho GTPases and their effector proteins.

Authors:  A L Bishop; A Hall
Journal:  Biochem J       Date:  2000-06-01       Impact factor: 3.857

2.  Arabidopsis RopGAPs are a novel family of rho GTPase-activating proteins that require the Cdc42/Rac-interactive binding motif for rop-specific GTPase stimulation.

Authors:  G Wu; H Li; Z Yang
Journal:  Plant Physiol       Date:  2000-12       Impact factor: 8.340

3.  The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function.

Authors:  Xiaoyu Li; Xia Bu; Binfeng Lu; Hava Avraham; Richard A Flavell; Bing Lim
Journal:  Mol Cell Biol       Date:  2002-02       Impact factor: 4.272

Review 4.  Clostridial toxins: molecular probes of Rho-dependent signaling and apoptosis.

Authors:  D A Bobak
Journal:  Mol Cell Biochem       Date:  1999-03       Impact factor: 3.396

5.  Plant Rac-like GTPases are activated by auxin and mediate auxin-responsive gene expression.

Authors:  Li-zhen Tao; Alice Y Cheung; Hen-ming Wu
Journal:  Plant Cell       Date:  2002-11       Impact factor: 11.277

6.  p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling.

Authors:  Takanobu Nakazawa; Ayako M Watabe; Tohru Tezuka; Yutaka Yoshida; Kazumasa Yokoyama; Hisashi Umemori; Akihiro Inoue; Shigeo Okabe; Toshiya Manabe; Tadashi Yamamoto
Journal:  Mol Biol Cell       Date:  2003-04-04       Impact factor: 4.138

7.  RAC GTPases in tobacco and Arabidopsis mediate auxin-induced formation of proteolytically active nuclear protein bodies that contain AUX/IAA proteins.

Authors:  Li-Zhen Tao; Alice Y Cheung; Candida Nibau; Hen-Ming Wu
Journal:  Plant Cell       Date:  2005-07-01       Impact factor: 11.277

8.  Structural basis of Robo proline-rich motif recognition by the srGAP1 Src homology 3 domain in the Slit-Robo signaling pathway.

Authors:  Xiaofeng Li; Yushu Chen; Yiwei Liu; Jia Gao; Feng Gao; Mark Bartlam; Jane Y Wu; Zihe Rao
Journal:  J Biol Chem       Date:  2006-07-20       Impact factor: 5.157

9.  The LIM domain-containing Dbm1 GTPase-activating protein is required for normal cellular morphogenesis in Saccharomyces cerevisiae.

Authors:  G C Chen; L Zheng; C S Chan
Journal:  Mol Cell Biol       Date:  1996-04       Impact factor: 4.272

10.  ZDS1 and ZDS2, genes whose products may regulate Cdc42p in Saccharomyces cerevisiae.

Authors:  E Bi; J R Pringle
Journal:  Mol Cell Biol       Date:  1996-10       Impact factor: 4.272
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