Literature DB >> 787015

Antiinflammatory drugs and gastrointestinal bleeding: a comparison of aspirin and ibuprofen.

F R Schmid, D D Culic.   

Abstract

Gastrointestinal blood loss provoked by short-term and long-term therapy with aspirin and ibuprofen was compared in patients with rheumatoid arthritis. Blood loss was assessed by isotope counting of four-day stool collections after infusion of 51Cr-labeled autologous erythrocytes. After two weeks on drug or after one year on drug, aspirin consistently caused more bleeding than ibuprofen.

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Year:  1976        PMID: 787015     DOI: 10.1002/j.1552-4604.1976.tb02416.x

Source DB:  PubMed          Journal:  J Clin Pharmacol        ISSN: 0091-2700            Impact factor:   3.126


  6 in total

1.  A procedure for measuring gastric bleeding caused by drugs.

Authors:  J N Hunt
Journal:  Dig Dis Sci       Date:  1979-07       Impact factor: 3.199

2.  A review of upper-gastrointestinal effects of the newer nonsteroidal antiinflammatory agents.

Authors:  R E Pemberton; L J Strand
Journal:  Dig Dis Sci       Date:  1979-01       Impact factor: 3.199

3.  Diflunisal: six-month experience in osteoarthritis.

Authors:  A Andrew; B Rodda; L Verhaest; C Van Winzum
Journal:  Br J Clin Pharmacol       Date:  1977-02       Impact factor: 4.335

4.  The effects of ibuprofen, indomethacin, aspirin, naproxen, and placebo on the gastric mucosa of normal volunteers: a gastroscopic and photographic study.

Authors:  F L Lanza; G L Royer; R S Nelson; T T Chen; C E Seckman; M F Rack
Journal:  Dig Dis Sci       Date:  1979-11       Impact factor: 3.199

Review 5.  Etodolac, a new nonsteroidal anti-inflammatory drug: gastrointestinal microbleeding and endoscopic studies.

Authors:  F L Lanza; J D Arnold
Journal:  Clin Rheumatol       Date:  1989-03       Impact factor: 2.980

Review 6.  Pain management for inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other spondylarthritis) and gastrointestinal or liver comorbidity.

Authors:  Helga Radner; Sofia Ramiro; Rachelle Buchbinder; Robert B M Landewé; Désirée van der Heijde; Daniel Aletaha
Journal:  Cochrane Database Syst Rev       Date:  2012-01-18
  6 in total

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