Literature DB >> 7869995

Design of a high-flux epithermal neutron beam using 235U fission plates at the Brookhaven Medical Research Reactor.

H B Liu1, R M Brugger, D C Rorer, P R Tichler, J P Hu.   

Abstract

Beams of epithermal neutrons are being used in the development of boron neutron capture therapy for cancer. This report describes a design study in which 235U fission plates and moderators are used to produce an epithermal neutron beam with higher intensity and better quality than the beam currently in use at the Brookhaven Medical Research Reactor (BMRR). Monte Carlo calculations are used to predict the neutron and gamma fluxes and absorbed doses produced by the proposed design. Neutron flux measurements at the present epithermal treatment facility (ETF) were made to verify and compare with the computed results where feasible. The calculations indicate that an epithermal neutron beam produced by a fission-plate converter could have an epithermal neutron intensity of 1.2 x 10(10) n/cm2.s and a fast neutron dose per epithermal neutron of 2.8 x 10(-11) cGy.cm2/nepi plus being forward directed. This beam would be built into the beam shutter of the ETF at the BMRR. The feasibility of remodeling the facility is discussed.

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Year:  1994        PMID: 7869995     DOI: 10.1118/1.597268

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  2 in total

Review 1.  The rationale and requirements for the development of boron neutron capture therapy of brain tumors.

Authors:  A H Soloway; R F Barth; R A Gahbauer; T E Blue; J H Goodman
Journal:  J Neurooncol       Date:  1997-05       Impact factor: 4.130

Review 2.  The requirements and development of neutron beams for neutron capture therapy of brain cancer.

Authors:  R L Moss; O Aizawa; D Beynon; R Brugger; G Constantine; O Harling; H B Liu; P Watkins
Journal:  J Neurooncol       Date:  1997-05       Impact factor: 4.130

  2 in total

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