Literature DB >> 7869877

Osteoarthritis of the knee and associated factors of age and obesity: effects on gait.

S P Messier1.   

Abstract

1) A majority of people afflicted with osteoarthritis (OA) of the knee are elderly and many have their OA exacerbated by obesity. 2) Healthy older adults exhibit gait patterns that differ from a healthy, younger cohort. These differences include a slower walking velocity, slower cadence, shorter step length, reduced hip and knee range of motion, and greater stride width, vertical oscillation, and lateral sway of the head. 3) Subjects afflicted with knee OA have decreased knee range of motion and knee angular velocity, increased loading rate on the less affected leg, and a compensatory increase in hip angular velocity when compared with age matched healthy subjects. 4) Obesity, which is strongly associated with knee OA, increases rearfoot motion during walking and causes the forefoot to abduct significantly more than in normal weight individuals.

Entities:  

Mesh:

Year:  1994        PMID: 7869877

Source DB:  PubMed          Journal:  Med Sci Sports Exerc        ISSN: 0195-9131            Impact factor:   5.411


  35 in total

Review 1.  Obesity: a preventable risk factor for large joint osteoarthritis which may act through biomechanical factors.

Authors:  A Powell; A J Teichtahl; A E Wluka; F M Cicuttini
Journal:  Br J Sports Med       Date:  2005-01       Impact factor: 13.800

2.  Effects of obesity on posture and walking: study prior to and following surgically induced weight loss.

Authors:  M L Ponta; M Gozza; J Giacinto; R Gradaschi; G F Adami
Journal:  Obes Surg       Date:  2014-11       Impact factor: 4.129

Review 3.  Combating osteoporosis and obesity with exercise: leveraging cell mechanosensitivity.

Authors:  Gabriel M Pagnotti; Maya Styner; Gunes Uzer; Vihitaben S Patel; Laura E Wright; Kirsten K Ness; Theresa A Guise; Janet Rubin; Clinton T Rubin
Journal:  Nat Rev Endocrinol       Date:  2019-06       Impact factor: 43.330

Review 4.  Biomechanical factors in osteoarthritis.

Authors:  Farshid Guilak
Journal:  Best Pract Res Clin Rheumatol       Date:  2011-12       Impact factor: 4.098

5.  Pre- to postoperative changes in physical activity: report from the longitudinal assessment of bariatric surgery-2 (LABS-2).

Authors:  Wendy C King; Jesse Y Hsu; Steven H Belle; Anita P Courcoulas; George M Eid; David R Flum; James E Mitchell; John R Pender; Mark D Smith; Kristine J Steffen; Bruce M Wolfe
Journal:  Surg Obes Relat Dis       Date:  2011-08-16       Impact factor: 4.734

6.  Development and validation of a motion and loading system for a rat knee joint in vivo.

Authors:  Xiang Ian Gu; Daniel J Leong; Francisco Guzman; Rashal Mahamud; Yong Hui Li; Robert J Majeska; Mitchell B Schaffler; Hui Bin Sun; Luis Cardoso
Journal:  Ann Biomed Eng       Date:  2009-12-16       Impact factor: 3.934

7.  Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.

Authors:  Timothy M Griffin; Beverley Fermor; Janet L Huebner; Virginia B Kraus; Ramona M Rodriguiz; William C Wetsel; Li Cao; Lori A Setton; Farshid Guilak
Journal:  Arthritis Res Ther       Date:  2010-07-06       Impact factor: 5.156

8.  Physical activity and obesity: biomechanical and physiological key concepts.

Authors:  Julie Nantel; Marie-Eve Mathieu; François Prince
Journal:  J Obes       Date:  2010-11-22

9.  The relationship of self-reported pain and functional impairment to gait mechanics in overweight and obese persons with knee osteoarthritis.

Authors:  Mary Beth Nebel; Ershela L Sims; Francis J Keefe; Virginia B Kraus; Farshid Guilak; David S Caldwell; Jennifer J Pells; Robin Queen; Daniel Schmitt
Journal:  Arch Phys Med Rehabil       Date:  2009-11       Impact factor: 3.966

10.  Pain catastrophizing and pain-related fear in osteoarthritis patients: relationships to pain and disability.

Authors:  Tamara J Somers; Francis J Keefe; Jennifer J Pells; Kim E Dixon; Sandra J Waters; Paul A Riordan; James A Blumenthal; Daphne C McKee; Lara LaCaille; Jessica M Tucker; Daniel Schmitt; David S Caldwell; Virginia B Kraus; Ershela L Sims; Rebecca A Shelby; John R Rice
Journal:  J Pain Symptom Manage       Date:  2008-11-28       Impact factor: 3.612

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