| Literature DB >> 7868851 |
K Otani1, T Kondo, S Kaneko, M Ishida, Y Fukushima.
Abstract
The correlation between prolactin response and therapeutic effects of zotepine, as assessed by the Brief Psychiatric Rating Scale, was studied in 24 schizophrenic patients (12 males, 12 females), after 4 weeks of treatment. The daily dose was 100 mg in the first week, and 200 mg for the next 3 weeks. There were significant (p < 0.05) positive correlations between changes in serum prolactin concentration and amelioration scores of positive or total symptoms in males only. Thus, prolactin response may reflect therapeutic effects of zotepine, at least in males.Entities:
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Year: 1994 PMID： 7868851 DOI： 10.1097/00004850-199400940-00008
Source DB: PubMed Journal: Int Clin Psychopharmacol ISSN： 0268-1315 Impact factor: 1.659