| Literature DB >> 786880 |
Abstract
The distribution of dengue-2 antigens was studied in infected monkey kidney cells (LLC MK2) using an indirect, horseradish peroxidase-conjugated immunoglobulin technique. This procedure allowed both light and electron microscopic examination of serial-step sections of individual cells cut in a plane perpendicular to the monolayer. Both virion and nonvirion antigens were identified on the plasma membrane with this technique. A diffuse cytoplasmic reaction product was also present. The intensity and distribution of the cytoplasmic reaction product was related to disruption of the plasma membrane.Entities:
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Year: 1976 PMID: 786880 PMCID: PMC420822 DOI: 10.1128/iai.13.6.1699-1709.1976
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441