Literature DB >> 7868387

Darlucins A and B, new isocyanide antibiotics from Sphaerellopsis filum (Darluca filum).

S Zapf1, M Hossfeld, H Anke, R Velten, W Steglich.   

Abstract

Two new xanthocillin type antibiotics, darlucin A (1) and B (2), were isolated from fermentations of Sphaerellopsis filum (Darluca filum). Their structures were established by spectroscopic methods. The darlucins are the first known compounds with a 1,2-diisocyanoalkene moiety. Both compounds exhibited antibacterial, antifungal and weak cytotoxic activities.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7868387     DOI： 10.7164/antibiotics.48.36

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  4 in total

1.  A marine Mesorhizobium sp. produces structurally novel long-chain N-acyl-L-homoserine lactones.

Authors:  Anja Krick; Stefan Kehraus; Leo Eberl; Kathrin Riedel; Heidrun Anke; Ines Kaesler; Ingeborg Graeber; Ulrich Szewzyk; Gabriele M König
Journal:  Appl Environ Microbiol       Date:  2007-03-30       Impact factor: 4.792

2.  Evolution of new enzymatic function by structural modulation of cysteine reactivity in Pseudomonas fluorescens isocyanide hydratase.

Authors:  Mahadevan Lakshminarasimhan; Peter Madzelan; Ruth Nan; Nicole M Milkovic; Mark A Wilson
Journal:  J Biol Chem       Date:  2010-07-14       Impact factor: 5.157

3.  Tanzawaic acids I-L: Four new polyketides from Penicillium sp. IBWF104-06.

Authors:  Louis P Sandjo; Eckhard Thines; Till Opatz; Anja Schüffler
Journal:  Beilstein J Org Chem       Date:  2014-01-22       Impact factor: 2.883

4.  Broad Spectrum Antibiotic Xanthocillin X Effectively Kills Acinetobacter baumannii via Dysregulation of Heme Biosynthesis.

Authors:  Ines Hübner; Justin A Shapiro; Jörn Hoßmann; Jonas Drechsel; Stephan M Hacker; Philip N Rather; Dietmar H Pieper; William M Wuest; Stephan A Sieber
Journal:  ACS Cent Sci       Date:  2021-01-20       Impact factor: 14.553
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.