Literature DB >> 7866704

Mechanisms of sexual transmission of HIV: does HIV infect intact epithelia?

D M Phillips1, V R Zacharopoulos, X Tan, R Pearce-Pratt.   

Abstract

The prevailing view of sexual transmission of HIV has been that the virus enters the body through lesions in the epithelium of the genital tract. We propose that transmission of HIV can occur via the infection of intact epithelial cells, and that it is mediated by HIV-infected mononuclear cells in genital-tract secretions.

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Year:  1994        PMID： 7866704     DOI： 10.1016/0966-842x(94)90804-4

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  12 in total

Review 1.  Antiretroviral-drug concentrations in semen: implications for sexual transmission of human immunodeficiency virus type 1.

Authors:  A D Kashuba; J R Dyer; L M Kramer; R H Raasch; J J Eron; M S Cohen
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

Review 2.  Interactions between HIV-1 and mucosal cells in the female reproductive tract.

Authors:  Ruizhong Shen; Holly E Richter; Phillip D Smith
Journal:  Am J Reprod Immunol       Date:  2014-04-01       Impact factor: 3.886

3.  The membrane-proximal intracytoplasmic tyrosine residue of HIV-1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells.

Authors:  R Lodge; J P Lalonde; G Lemay; E A Cohen
Journal:  EMBO J       Date:  1997-02-17       Impact factor: 11.598

4.  Two distinct oncornaviruses harbor an intracytoplasmic tyrosine-based basolateral targeting signal in their viral envelope glycoprotein.

Authors:  R Lodge; L Delamarre; J P Lalonde; J Alvarado; D A Sanders; M C Dokhélar; E A Cohen; G Lemay
Journal:  J Virol       Date:  1997-07       Impact factor: 5.103

5.  Cell-mediated infection of cervix derived epithelial cells with primary isolates of human immunodeficiency virus.

Authors:  X Tan; D M Phillips
Journal:  Arch Virol       Date:  1996       Impact factor: 2.574

6.  Polarized human immunodeficiency virus budding in lymphocytes involves a tyrosine-based signal and favors cell-to-cell viral transmission.

Authors:  J Deschambeault; J P Lalonde; G Cervantes-Acosta; R Lodge; E A Cohen; G Lemay
Journal:  J Virol       Date:  1999-06       Impact factor: 5.103

7.  HIV-1-infected blood mononuclear cells form an integrin- and agrin-dependent viral synapse to induce efficient HIV-1 transcytosis across epithelial cell monolayer.

Authors:  Annette Alfsen; Huifeng Yu; Aude Magérus-Chatinet; Alain Schmitt; Morgane Bomsel
Journal:  Mol Biol Cell       Date:  2005-06-22       Impact factor: 4.138

8.  Directional budding of human immunodeficiency virus from monocytes.

Authors:  M E Perotti; X Tan; D M Phillips
Journal:  J Virol       Date:  1996-09       Impact factor: 5.103

Review 9.  Virology research and virulent human pandemics.

Authors:  C A Mims
Journal:  Epidemiol Infect       Date:  1995-12       Impact factor: 2.451

Review 10.  Selective transmission of R5 HIV-1 variants: where is the gatekeeper?

Authors:  Jean-Charles Grivel; Robin J Shattock; Leonid B Margolis
Journal:  J Transl Med       Date:  2011-01-27       Impact factor: 5.531
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