Literature DB >> 78645

Free and bound 5-S-cysteinyldopa and dopa in human malignant melanomas.

G Agrup, C Hansson, H Rorsman, A M Rosengren, E Rosengren.   

Abstract

Free dopa and 5-S-cysteinyldopa were extracted from two human melanomas. Subsequent hydrolysis of carefully washed melanoma tissue released dopa and 5-S-cysteinyldopa, indication the presence of these catechol amino acids in proteins. Cysteinyldopa-containing proteins may represent the antigens previously demonstrated in human melanomas.

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Year:  1978        PMID: 78645

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN: 0001-5555            Impact factor:   4.437


  1 in total

1.  Oxidation of tyrosine residues in proteins by tyrosinase. Formation of protein-bonded 3,4-dihydroxyphenylalanine and 5-S-cysteinyl-3,4-dihydroxyphenylalanine.

Authors:  S Ito; T Kato; K Shinpo; K Fujita
Journal:  Biochem J       Date:  1984-09-01       Impact factor: 3.857

  1 in total

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