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Literature DB >> 7863772

Pigmented villonodular synovitis. Monoclonality and metastasis--a case for neoplastic origin?

P F Choong¹, H Willén, M Nilbert, F Mertens, N Mandahl, B Carlén, A Rydholm.

Abstract

We report a 48-year follow-up of a case of recurrent pigmented villonodular synovitis of the knee. Subcutaneous metastasis to the contralateral thigh was an unusual finding. Histology demonstrated fibroblastic and histiocytic proliferation, as well as increased mitotic activity in recurrent lesions. Cytogenetic analyses demonstrated monoclonality and chromosomal abnormalities. Our findings support a neoplastic origin of this lesion.

Entities: Disease

Mesh：

Year: 1995 PMID： 7863772 DOI： 10.3109/17453679508994643

Source DB: PubMed Journal: Acta Orthop Scand ISSN： 0001-6470

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Cited

19 in total

1. Atypical and bilateral pigmented villonodular synovitis of wrist in an adolescent patient: case report and literature review.

Authors: Deqing Luo; Le Yu; Limin Yang; Qigan Zhu; Hongyue Ren; Hui Liu
Journal: Int J Clin Exp Pathol Date: 2021-03-01

10. Low-dose external beam radiotherapy as a postoperative treatment for patients with diffuse pigmented villonodular synovitis of the knee: 4 recurrences in 23 patients followed for mean 9 years.

Authors: Geumju Park; Young Seok Kim; Jong Hoon Kim; Sang-wook Lee; Si Yeol Song; Eun Kyung Choi; Seong Yoon Yi; Seung Do Ahn
Journal: Acta Orthop Date: 2012-04-11 Impact factor: 3.717

Pigmented villonodular synovitis. Monoclonality and metastasis--a case for neoplastic origin?

1. Atypical and bilateral pigmented villonodular synovitis of wrist in an adolescent patient: case report and literature review.

2. Giant cells in pigmented villo nodular synovitis express an osteoclast phenotype.

3. Pigmented villonodular synovitis of the knee in skeletally immature patients.

4. Multifocal PVNS in a child--followed over 25 years.

5. Malignant giant cell tumor in the carpal tunnel: a case report and review of literature.

6. Updates on the cytogenetics and molecular cytogenetics of benign and intermediate soft tissue tumors.

7. Treatment of diffuse pigmented villonodular synovitis of the knee with combined surgical and radiosynovectomy.

8. Molecular cytogenetic characterization of tenosynovial giant cell tumors.

9. Postsurgical paracicatricial cutaneous satellitosis of giant cell tumour of the tendon sheath, localized type.

10. Low-dose external beam radiotherapy as a postoperative treatment for patients with diffuse pigmented villonodular synovitis of the knee: 4 recurrences in 23 patients followed for mean 9 years.