PURPOSE: To correlate the magnetic resonance (MR) imaging features of and histologic findings in Lhermitte-Duclos disease (LDD) (dysplastic gangliocytoma). MATERIALS AND METHODS: MR imaging and histologic data from eight patients with the diagnosis of LDD were retrospectively reviewed. Gross pathologic specimens were also available in one case. Contrast material-enhanced MR images were obtained in seven of the eight patients. RESULTS: At MR imaging, a non-enhancing mass in the cerebellar hemisphere was characterized by a striated pattern of hyperintensity on T2-weighted images and corresponding hypointensity on T1-weighted images, which represented the abnormally thickened folia. None of the masses demonstrated enhancement. CONCLUSION: Most other cerebellar masses destroy the folial pattern and show enhancement. The nonenhancing striated MR appearance of thickened folia in patients with LDD is distinctive and should suggest this diagnosis.
PURPOSE: To correlate the magnetic resonance (MR) imaging features of and histologic findings in Lhermitte-Duclos disease (LDD) (dysplastic gangliocytoma). MATERIALS AND METHODS: MR imaging and histologic data from eight patients with the diagnosis of LDD were retrospectively reviewed. Gross pathologic specimens were also available in one case. Contrast material-enhanced MR images were obtained in seven of the eight patients. RESULTS: At MR imaging, a non-enhancing mass in the cerebellar hemisphere was characterized by a striated pattern of hyperintensity on T2-weighted images and corresponding hypointensity on T1-weighted images, which represented the abnormally thickened folia. None of the masses demonstrated enhancement. CONCLUSION: Most other cerebellar masses destroy the folial pattern and show enhancement. The nonenhancing striated MR appearance of thickened folia in patients with LDD is distinctive and should suggest this diagnosis.
Authors: J Klisch; F Juengling; J Spreer; D Koch; T Thiel; M Büchert; S Arnold; F Feuerhake; M Schumacher Journal: AJNR Am J Neuroradiol Date: 2001-05 Impact factor: 3.825
Authors: Christoph Moenninghoff; Oliver Kraff; Marc Schlamann; Mark E Ladd; Zaza Katsarava; Elke R Gizewski Journal: Korean J Radiol Date: 2010-02-22 Impact factor: 3.500
Authors: L Spaargaren; P Cras; M A M Bomhof; S T Lie; A M de Barsy; P H Croese; J L J M Teepen; V H J M Duwel; J W Van Goethem; O Ozsarlak; L van den Hauwe; A M De Schepper; P M Parizel Journal: Neuroradiology Date: 2003-05-16 Impact factor: 2.804