Literature DB >> 7862269

Event-related potential amplitude/intensity slopes predict response to antidepressants.

S R Paige1, D F Fitzpatrick, J P Kline, S E Balogh, S E Hendricks.   

Abstract

We measured event-related potential (ERP) component amplitudes to four intensities of randomly presented tones. Patients diagnosed with major depressive disorder were tested prior to and following a clinical trial of antidepressant medication. Slope of P2 amplitude as a function of stimulus intensity was calculated for each subject and condition. Subjects were divided into two groups (responders and nonresponders) based on their Hamilton Rating Scale for depression scores following treatment. Responders had significantly larger P2 slopes prior to treatment than did nonresponders. P2 slopes did not differ significantly between responders and nonresponders following antidepressant treatment. These data support the conclusion that P2 amplitude/intensity slope may be a predictor of response to treatment with antidepressant medication.

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Year:  1994        PMID： 7862269     DOI： 10.1159/000119161

Source DB:  PubMed          Journal:  Neuropsychobiology        ISSN： 0302-282X            Impact factor:   2.328


  9 in total

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5.  Demonstrating test-retest reliability of electrophysiological measures for healthy adults in a multisite study of biomarkers of antidepressant treatment response.

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6.  Loudness dependence of the auditory evoked potential and response to antidepressants in Chinese patients with major depression.

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Journal:  J Psychiatry Neurosci       Date:  2005-05       Impact factor: 6.186

7.  Hemispatial PCA dissociates temporal from parietal ERP generator patterns: CSD components in healthy adults and depressed patients during a dichotic oddball task.

Authors:  Craig E Tenke; Jürgen Kayser; Stewart A Shankman; Carlye B Griggs; Paul Leite; Jonathan W Stewart; Gerard E Bruder
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8.  Response prediction to antidepressants using scalp and source-localized loudness dependence of auditory evoked potential (LDAEP) slopes.

Authors:  Natalia Jaworska; Claude Blondeau; Pierre Tessier; Sandhaya Norris; Wendy Fusee; Pierre Blier; Verner Knott
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Review 9.  Predictors, moderators, and mediators (correlates) of treatment outcome in major depressive disorder.

Authors:  George I Papakostas; Maurizio Fava
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  9 in total

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