Sperm-induced urolithiasis in the rat.

Experiments are described demonstrating that experimental insemination with autologous or homologous sperm into the ventral prostate or bladder neck of outbred Zbar male rats induces intravesical precipitation or stones. These observations suggest that clinical conditions resulting in intravesical sperm may be contributory to bladder lithiasis in man and may have relevance to its prevalence in men vs. women.