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Literature DB >> 7858069

Temporal lobe abnormalities in multigenerational families with schizophrenia.

W G Honer¹, A S Bassett, G N Smith, J S Lapointe, P Falkai.

Abstract

Brain structure in familial schizophrenia was studied with computerized tomography in 42 individuals from six multigenerational families. Sulcal enlargement in the lateral temporal cortex, and ventricular and cisternal enlargement in the medial temporal region were observed in psychotic individuals compared to unaffected family members. Genetic factors in familial schizophrenia may exert part of their effect through determining or altering temporal lobe structure.

Entities: Disease

Mesh：

Year: 1994 PMID： 7858069 PMCID： PMC3160970 DOI： 10.1016/0006-3223(94)90084-1

Source DB: PubMed Journal: Biol Psychiatry ISSN： 0006-3223 Impact factor: 13.382

28 in total

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Authors: R L Suddath; G W Christison; E F Torrey; M F Casanova; D R Weinberger
Journal: N Engl J Med Date: 1990-03-22 Impact factor: 91.245

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Authors: W G Honer; A S Bassett; L Kopala; J L Kennedy
Journal: Can J Psychiatry Date: 1990-12 Impact factor: 4.356

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Authors: I D Dauphinais; L E DeLisi; T J Crow; K Alexandropoulos; N Colter; I Tuma; E S Gershon
Journal: Psychiatry Res Date: 1990-12 Impact factor: 3.222

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Authors: S R Kay; A Fiszbein; L A Opler
Journal: Schizophr Bull Date: 1987 Impact factor: 9.306

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Authors: P E Barta; G D Pearlson; R E Powers; S S Richards; L E Tune
Journal: Am J Psychiatry Date: 1990-11 Impact factor: 18.112

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Authors: H Kaiya; M Uematsu; M Ofuji; A Nishida; M Morikiyo; S Adachi
Journal: Br J Psychiatry Date: 1989-10 Impact factor: 9.319

7. Genetic and perinatal determinants of structural brain deficits in schizophrenia.

Authors: T D Cannon; S A Mednick; J Parnas
Journal: Arch Gen Psychiatry Date: 1989-10

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Authors: D H Blackwood; D M St Clair; W J Muir; J C Duffy
Journal: Arch Gen Psychiatry Date: 1991-10

9. Codistribution of a sensory gating deficit and schizophrenia in multi-affected families.

Authors: M C Waldo; G Carey; M Myles-Worsley; E Cawthra; L E Adler; H T Nagamoto; P Wender; W Byerley; R Plaetke; R Freedman
Journal: Psychiatry Res Date: 1991-12 Impact factor: 3.222

10. [Brain substance deficit with paralimbic and limbic involvement in computerized tomography studies of schizophrenic patients].

Authors: B Bogerts; C Wurthmann; H D Piroth
Journal: Nervenarzt Date: 1987-02 Impact factor: 1.214

6 in total

6. A study of hippocampal shape anomaly in schizophrenia and in families multiply affected by schizophrenia or bipolar disorder.

Authors: S E J Connor; V Ng; C McDonald; K Schulze; K Morgan; P Dazzan; R M Murray
Journal: Neuroradiology Date: 2004-06-15 Impact factor: 2.804