Literature DB >> 7857990

The bisindolylmaleimide GF 109203X, a selective inhibitor of protein kinase C, does not inhibit the potentiating effect of phorbol ester on ethanol-induced phospholipase C-mediated hydrolysis of phosphatidylethanolamine.

Z Kiss1, H Phillips, W H Anderson.   

Abstract

In fibroblasts, the protein kinase C (PKC) activator phorbol 12-myristate (PMA) either inhibits or stimulates phospholipase C-mediated hydrolysis of phosphatidylethanolamine in the absence or presence of ethanol, respectively. Here, we demonstrate that the specific PKC inhibitor bisindolylmaleimide GF 109203X prevents only the inhibitory, but not the stimulatory, PMA effect.

Entities:  

Mesh：

Substances：

Year:  1995        PMID： 7857990     DOI： 10.1016/0167-4889(94)00242-7

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  Signaling cascades triggered by bacterial metabolic end products during reactivation of Kaposi's sarcoma-associated herpesvirus.

Authors:  T L Morris; R R Arnold; J Webster-Cyriaque
Journal:  J Virol       Date:  2007-03-21       Impact factor: 5.103

2.  EGFR signals to mTOR through PKC and independently of Akt in glioma.

Authors:  Qi-Wen Fan; Christine Cheng; Zachary A Knight; Daphne Haas-Kogan; David Stokoe; C David James; Frank McCormick; Kevan M Shokat; William A Weiss
Journal:  Sci Signal       Date:  2009-01-27       Impact factor: 8.192

3.  Role of protein kinase C delta in reactivation of Kaposi's sarcoma-associated herpesvirus.

Authors:  Einat Deutsch; Adina Cohen; Gila Kazimirsky; Sara Dovrat; Hadara Rubinfeld; Chaya Brodie; Ronit Sarid
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

4.  Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology.

Authors:  F Wang; V M Weaver; O W Petersen; C A Larabell; S Dedhar; P Briand; R Lupu; M J Bissell
Journal:  Proc Natl Acad Sci U S A       Date:  1998-12-08       Impact factor: 11.205

5.  Protein kinase C delta blocks immediate-early gene expression in senescent cells by inactivating serum response factor.

Authors:  Keith Wheaton; Karl Riabowol
Journal:  Mol Cell Biol       Date:  2004-08       Impact factor: 4.272

6.  Choline derived from the phosphatidylcholine specific phospholipase D is not directly available for the CDP choline pathway in phorbol ester-treated C3H10T1/2 Cl 8 fibroblasts.

Authors:  V A Thorsen; O Bruland; J R Lillehaug; H Holmsen
Journal:  Mol Cell Biochem       Date:  1998-10       Impact factor: 3.396

7.  Multiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5.

Authors:  Christine Doucet; Gustavo J Gutierrez; Catherine Lindon; Thierry Lorca; Gwendaline Lledo; Christian Pinset; Olivier Coux
Journal:  BMC Biochem       Date:  2005-12-01       Impact factor: 4.059

8.  Bacteria induce prolonged PMN survival via a phosphatidylcholine-specific phospholipase C- and protein kinase C-dependent mechanism.

Authors:  Saskia F Erttmann; Nelson O Gekara; Maria Fällman
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.