Literature DB >> 7856080

The UL37 protein of herpes simplex virus type 1 is associated with the tegument of purified virions.

J B Schmitz1, A G Albright, P R Kinchington, F J Jenkins.   

Abstract

The herpes simplex virus type 1 (HSV-1) UL37 open reading frame encodes a 120-kDa late (gamma 1) phosphoprotein in infected cells. Analysis of isolated mature HSV virions and light particles revealed that the UL37 protein is a component of the virion. Detergent solubilization and protease digestion experiments suggest that the UL37 protein is part of the tegument structure. Indirect immunofluorescence experiments using HSV-1-infected cells and cells infected with a vaccinia recombinant virus that expresses the UL37 gene demonstrated that the UL37 protein is present in both the nucleus and cytoplasm of infected cells and that localization to the nucleus does not require additional HSV proteins.

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Year:  1995        PMID: 7856080     DOI: 10.1006/viro.1995.1028

Source DB:  PubMed          Journal:  Virology        ISSN: 0042-6822            Impact factor:   3.616


  32 in total

1.  The role of the cytoskeleton in the life cycle of viruses and intracellular bacteria: tracks, motors, and polymerization machines.

Authors:  E L Bearer; P Satpute-Krishnan
Journal:  Curr Drug Targets Infect Disord       Date:  2002-09

2.  Herpes simplex virus type 1 tegument proteins VP1/2 and UL37 are associated with intranuclear capsids.

Authors:  Michelle A Bucks; Kevin J O'Regan; Michael A Murphy; John W Wills; Richard J Courtney
Journal:  Virology       Date:  2007-01-16       Impact factor: 3.616

3.  Comprehensive characterization of extracellular herpes simplex virus type 1 virions.

Authors:  Sandra Loret; Ginette Guay; Roger Lippé
Journal:  J Virol       Date:  2008-07-02       Impact factor: 5.103

4.  Phenylalanine residues at the carboxyl terminus of the herpes simplex virus 1 UL20 membrane protein regulate cytoplasmic virion envelopment and infectious virus production.

Authors:  Anu-Susan Charles; Vladimir N Chouljenko; Nithya Jambunathan; Ramesh Subramanian; Peter Mottram; Konstantin G Kousoulas
Journal:  J Virol       Date:  2014-04-23       Impact factor: 5.103

Review 5.  Herpesviruses remodel host membranes for virus egress.

Authors:  David C Johnson; Joel D Baines
Journal:  Nat Rev Microbiol       Date:  2011-05       Impact factor: 60.633

6.  Immediate-early protein ME53 forms foci and colocalizes with GP64 and the major capsid protein VP39 at the cell membranes of Autographa californica multiple nucleopolyhedrovirus-infected cells.

Authors:  Jondavid de Jong; David A Theilmann; Basil M Arif; Peter J Krell
Journal:  J Virol       Date:  2011-07-20       Impact factor: 5.103

7.  Identification of interaction domains within the UL37 tegument protein of herpes simplex virus type 1.

Authors:  Michelle A Bucks; Michael A Murphy; Kevin J O'Regan; Richard J Courtney
Journal:  Virology       Date:  2011-05-20       Impact factor: 3.616

8.  Complex mechanisms for the packaging of the UL16 tegument protein into herpes simplex virus.

Authors:  David G Meckes; Jacob A Marsh; John W Wills
Journal:  Virology       Date:  2010-01-03       Impact factor: 3.616

9.  Plus- and minus-end directed microtubule motors bind simultaneously to herpes simplex virus capsids using different inner tegument structures.

Authors:  Kerstin Radtke; Daniela Kieneke; André Wolfstein; Kathrin Michael; Walter Steffen; Tim Scholz; Axel Karger; Beate Sodeik
Journal:  PLoS Pathog       Date:  2010-07-08       Impact factor: 6.823

10.  Localization of herpes simplex virus type 1 UL37 in the Golgi complex requires UL36 but not capsid structures.

Authors:  Prashant Desai; Gerry L Sexton; Eugene Huang; Stanley Person
Journal:  J Virol       Date:  2008-09-10       Impact factor: 5.103

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