Literature DB >> 7855597

A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.

P Szankasi1, G R Smith.   

Abstract

Exonuclease I (Exo I) from Schizosaccharomyces pombe, a 5'-->3' double-stranded DNA exonuclease, is induced during meiotic prophase I. The exo1 gene is a member of a family of related DNA repair genes, including RAD2/rad13/xpgc and YKL510/rad2, conserved from yeast to humans. An exo1 mutant displays a mutator phenotype and alters activity of the ade6-M387 marker effect. These results suggest that Exo I acts in a pathway that corrects mismatched base pairs.

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Year:  1995        PMID： 7855597     DOI： 10.1126/science.7855597

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  94 in total

1.  A Uve1p-mediated mismatch repair pathway in Schizosaccharomyces pombe.

Authors:  B Kaur; J L Fraser; G A Freyer; S Davey; P W Doetsch
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

2.  Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1.

Authors:  G Pedrazzi; C Perrera; H Blaser; P Kuster; G Marra; S L Davies; G H Ryu; R Freire; I D Hickson; J Jiricny; I Stagljar
Journal:  Nucleic Acids Res       Date:  2001-11-01       Impact factor: 16.971

3.  Interactions of Exo1p with components of MutLalpha in Saccharomyces cerevisiae.

Authors:  P T Tran; J A Simon; R M Liskay
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-31       Impact factor: 11.205

4.  In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair.

Authors:  V Burdett; C Baitinger; M Viswanathan; S T Lovett; P Modrich
Journal:  Proc Natl Acad Sci U S A       Date:  2001-05-29       Impact factor: 11.205

5.  Control of GT repeat stability in Schizosaccharomyces pombe by mismatch repair factors.

Authors:  A A Mansour; C Tornier; E Lehmann; M Darmon; O Fleck
Journal:  Genetics       Date:  2001-05       Impact factor: 4.562

6.  EXO1 and MSH6 are high-copy suppressors of conditional mutations in the MSH2 mismatch repair gene of Saccharomyces cerevisiae.

Authors:  T Sokolsky; E Alani
Journal:  Genetics       Date:  2000-06       Impact factor: 4.562

7.  hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci.

Authors:  H E Kleczkowska; G Marra; T Lettieri; J Jiricny
Journal:  Genes Dev       Date:  2001-03-15       Impact factor: 11.361

8.  Alteration of gene conversion tract length and associated crossing over during plasmid gap repair in nuclease-deficient strains of Saccharomyces cerevisiae.

Authors:  L S Symington; L E Kang; S Moreau
Journal:  Nucleic Acids Res       Date:  2000-12-01       Impact factor: 16.971

9.  mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.

Authors:  David N Everly; Pinghui Feng; I Saira Mian; G Sullivan Read
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

10.  Fission yeast Dna2 is required for generation of the telomeric single-strand overhang.

Authors:  Kazunori Tomita; Tatsuya Kibe; Ho-Young Kang; Yeon-Soo Seo; Masahiro Uritani; Takashi Ushimaru; Masaru Ueno
Journal:  Mol Cell Biol       Date:  2004-11       Impact factor: 4.272
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